Early cytotoxic effects of ochratoxin A in rat liver: A morphological, biochemical and molecular study
N Gagliano, I Dalle Donne, C Torri, M Migliori, F Grizzi… - Toxicology, 2006 - Elsevier
We characterized the overall early effect of chronic ochratoxin A (OTA) treatment on rat liver,
analyzing different aspects related to:(i) fibrosis, by measuring collagen content and …
analyzing different aspects related to:(i) fibrosis, by measuring collagen content and …
Toxicities induced in cultured human hepatocarcinoma cells exposed to ochratoxin A: oxidative stress and apoptosis status
EE Golli Bennour… - … of Biochemical and …, 2009 - Wiley Online Library
Ochratoxin A (OTA) is a mycotoxin currently detected in stored animal and human food
supplies as well as in human sera worldwide. OTA has diverse toxicological effects; …
supplies as well as in human sera worldwide. OTA has diverse toxicological effects; …
[HTML][HTML] Ochratoxin A induces oxidative stress in HepG2 Cells by impairing the gene expression of antioxidant enzymes
Ochratoxin A (OTA) is a mycotoxin frequently found in raw and processed foods. While it is
considered a possible human carcinogen, the mechanism of action remains unclear. OTA …
considered a possible human carcinogen, the mechanism of action remains unclear. OTA …
Ochratoxin a lowers mRNA levels of genes encoding for key proteins of liver cell metabolism
C Hundhausen, C Boesch-Saadatmandi… - Cancer Genomics & …, 2008 - cgp.iiarjournals.org
Ochratoxin A (OTA) is a nephro-and hepatotoxic mycotoxin that frequently contaminates
food and feedstuffs. Although recent studies have indicated that OTA modulates renal gene …
food and feedstuffs. Although recent studies have indicated that OTA modulates renal gene …
Characterization of ochratoxin A-induced apoptosis in primary rat hepatocytes
M Chopra, P Link, C Michels, D Schrenk - Cell biology and toxicology, 2010 - Springer
The main target organ of the mycotoxin ochratoxin A (OTA) in mammals is the kidney but
OTA has also been shown to be hepatotoxic in rats and to induce tumors in mouse liver …
OTA has also been shown to be hepatotoxic in rats and to induce tumors in mouse liver …
Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin A
M Marin-Kuan, V Ehrlich, T Delatour… - Journal of …, 2011 - Wiley Online Library
The in vitro and in vivo evidence compatible with a role for oxidative stress in OTA
carcinogenicity has been collected and described. Several potential oxido‐reduction …
carcinogenicity has been collected and described. Several potential oxido‐reduction …
Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line
Epidemiological studies have implicated ochratoxin A (OTA), a fungal metabolic-
contaminant of animal and human food sources, in Balkan Endemic Nephropathy and renal …
contaminant of animal and human food sources, in Balkan Endemic Nephropathy and renal …
[HTML][HTML] Toxicity of ochratoxin A and its modulation by antioxidants: A review
Ochratoxin A (OTA) is a mycotoxin involved in the development of different types of cancers
in rats, mice and humans. A growing number of in vitro and in vivo studies has been …
in rats, mice and humans. A growing number of in vitro and in vivo studies has been …
Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats
HG Kamp, G Eisenbrand, C Janzowski… - Molecular nutrition & …, 2005 - Wiley Online Library
The nephrotoxic/carcinogenic mycotoxin ochratoxin A (OTA) occurs as a contaminant in food
and feed and may be linked to human endemic Balkan nephropathy. The mechanism of …
and feed and may be linked to human endemic Balkan nephropathy. The mechanism of …
Oxidative damage and stress response from ochratoxin A exposure in rats
JC Gautier, D Holzhaeuser, J Markovic… - Free Radical Biology …, 2001 - Elsevier
Ochratoxin A (OTA) is a mycotoxin found in some cereal and grain products. It is a potent
renal carcinogen in male rats, although its mode of carcinogenic action is not known …
renal carcinogen in male rats, although its mode of carcinogenic action is not known …