Transfusion futility thresholds and mortality in geriatric trauma: Does frailty matter?

JC L'Huillier, S Hua, HJ Logghe, J Yu… - The American Journal of …, 2024 - Elsevier
Background Data on massive transfusion (MT) in geriatric trauma patients is lacking. This
study aims to determine geriatric transfusion futility thresholds (TT) and TT variations based …

The Magic Number 63-Redefining the Geriatric Age for Massive Transfusion in Trauma

JC L'Huillier, HJ Logghe, S Hua, AA Myneni… - Journal of Surgical …, 2024 - Elsevier
Introduction The arbitrary geriatric age cutoff of 65 may not accurately define older adults at
higher risk of mortality following massive transfusion (MT). We sought to redefine a new …

Death by decade: establishing a transfusion ceiling for futility in massive transfusion

MC Morris, GM Niziolek, JE Baker, BR Huebner… - journal of surgical …, 2020 - Elsevier
Background Age and massive transfusion are predictors of mortality after trauma. We
hypothesized that increasing age and high-volume transfusion would result in progressively …

Massive blood transfusions post trauma in the elderly compared to younger patients

B Mitra, A Olaussen, PA Cameron, T O'Donohoe… - Injury, 2014 - Elsevier
Introduction Older age and blood transfusion have both been independently associated with
higher mortality post trauma and the combination is expected to be associated with …

Analysis of transfusion volumes in the elderly trauma population

MA Guerrero, M Sridhar, S Yee, J Miller… - Journal of Current …, 2019 - currentsurgery.org
Background: Blood transfusion and old age have been independently associated with worse
outcomes and higher mortality in the trauma population. Determining specific volumes and …

Massive blood transfusion following older adult trauma: The effect of blood ratios on mortality

RD Hohle, JK Wothe, BM Hillmann… - Academic …, 2022 - Wiley Online Library
Background Massive blood transfusion (MBT) following older adult trauma poses unique
challenges. Despite extensive evidence on optimal resuscitative strategies in the younger …

Restrictive transfusion in geriatric trauma patients

AN Deleon, JM Uecker, SV Stafford, S Ali… - The American …, 2016 - journals.sagepub.com
To determine whether a restrictive strategy of red cell transfusion was safe in elderly trauma
patients, we compared those treated with a restrictive transfusion strategy versus those who …

Early predictors for massive transfusion in older adult severe trauma patients

T Ohmori, T Kitamura, J Ishihara, H Onishi, T Nojima… - Injury, 2017 - Elsevier
Background Many scoring systems for the early prediction of the need for massive
transfusion (MT) have been reported; in most of these, vital signs are regarded as important …

Transfusions in the less severely injured: does age of transfused blood affect outcomes?

JA Weinberg, G McGwin Jr, MB Marques… - Journal of Trauma …, 2008 - journals.lww.com
Background: Prior studies have demonstrated that transfusion of older stored blood is
associated with an increased risk of multiple organ failure, infection, and death. These …

Age of red blood cells is not associated with in-hospital mortality in massively transfused patients

NH Saadah, EM Wood, MJ Bailey… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Studies comparing mortality following massive transfusion (MT) with fresher
versus longer-stored red blood cells (RBCs) have focused on trauma patients. The …