Simple Summary Lateralized overgrowth may be isolated or accompany syndromes.
Recently, international BWS consensus proposed that the patients with isolated lateralized …

The congenital imprinting disorder, Beckwith‐Wiedemann syndrome (BWS) is associated
with variable clinical features including hemihypertrophy/lateralised overgrowth (LO) and …

Beckwith‐Wiedemann syndrome (BWS) is the most common epigenetic overgrowth and
cancer predisposition disorder. Due to both varying molecular defects involving …

Genomic imprinting plays an important role in mammalian development. Loss of imprinting
(LOI) through loss (LOM) or gain (GOM) of methylation is involved in many human disorders …

Lateralized overgrowth (LO), or segmental overgrowth, is defined as an increase in growth
of tissue (bone, muscle, connective tissue, vasculature, etc.) in any region of the body. Some …

Simple Summary Epigenetics encompasses changes in DNA without changing the DNA
sequence itself, and it includes, among other modifications, DNA methylation. DNA …

Abstract Background Beckwith–Wiedemann syndrome (BWS) is a rare overgrowth
syndrome characterized by congenital malformations and predisposition to embryonic …

Background: Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated
with an increased risk of pediatric tumors. The underlying molecular abnormalities may be …

Objective To compare tumor risk in the 4 Beckwith-Wiedemann syndrome (BWS) molecular
subgroups: Imprinting Control Region 1 Gain of Methylation (ICR1-GoM), Imprinting Control …

Abstract Beckwith–Wiedemann Syndrome (BWS) is an overgrowth syndrome caused by a
variety of molecular changes on chromosome 11p15. 5. Children with BWS have a …