T-regulatory cells (Tregs) represent a unique subpopulation of helper T-cells by maintaining
immune equilibrium using various mechanisms. The role of T-cell receptors (TCR) in …

Regulatory T cells (TReg cells), a specialized T cell lineage, have a pivotal function in the
control of self tolerance and inflammatory responses. Recent studies have revealed a …

The distinction between innate and adaptive immunity is one of the basic tenets of
immunology. The co-operation between these two arms of the immune system is a major …

Summary Foxp3+ CD4+ regulatory T cells (Tregs) are an immune cell lineage endowed with
immunosuppressive functionality in a wide array of contexts, including both anti‐pathogenic …

Naturally occurring CD4+ regulatory T cells (Tregs), which specifically express the
transcription factor FoxP3 in the nucleus and CD25 and CTLA-4 on the cell surface, are a …

Regulatory T cells (Tregs) play an indispensable role in maintaining immunological
unresponsiveness to self-antigens and in suppressing excessive immune responses …

Regulatory T cells (Tregs) are crucial mediators of self-tolerance in the periphery. They
differentiate in the thymus, where interactions with thymus-resident antigen-presenting cells …

Regulatory T (Treg) cells maintain immune homeostasis and prevent inflammatory and
autoimmune responses. During development, thymocytes bearing a moderately self-reactive …

The development of regulatory T (Treg) cells is essential for the maintenance of immune
tolerance and homeostasis. Here, we review recent studies that have advanced our …

Regulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the
dominant control of immunological tolerance and maintenance of immune homeostasis …