Sheep models of intrauterine growth restriction: fetal adaptations and consequences

JL Morrison - Clinical and Experimental Pharmacology and …, 2008 - Wiley Online Library
SUMMARY 1 Intrauterine growth restriction (IUGR) has been associated with poor perinatal
health outcomes. Animal models have been used to investigate why IUGR is associated with …

Investigating the causes of low birth weight in contrasting ovine paradigms

JM Wallace, TRH Regnault… - The Journal of …, 2005 - Wiley Online Library
Intrauterine growth restriction (IUGR) still accounts for a large incidence of infant mortality
and morbity worldwide. Many of the circulatory and transport properties of the sheep …

An animal model of placental insufficiency-induced intrauterine growth restriction

JS Barry, PJ Rozance, RV Anthony - Seminars in perinatology, 2008 - Elsevier
Intrauterine growth restriction (IUGR), often associated with functional placental
insufficiency, results in increased perinatal mortality and morbidity. For obvious reasons …

[PDF][PDF] Ruminant models of prenatal growth restriction

TRH Regnault - Reproduction, 2003 - biosciproceedings.org
Intrauterine growth restriction(IUGR) is a significant health issue that not only affects infant
mortality and morbidity, but may also predispose individuals to coronary heart disease …

Models of Intrauterine growth restriction and fetal programming in rabbits

J Lopez‐Tello, M Arias‐Alvarez… - Molecular …, 2019 - Wiley Online Library
Intrauterine growth restriction (IUGR) affects approximately 10% of human pregnancies
globally and has immediate and life‐long consequences for offspring health. However, the …

Fetal growth restriction and consequences for the offspring in animal models

K Holemans, L Aerts… - Journal of the Society for …, 2003 - journals.sagepub.com
Objective: In the present review we discuss rat models in which intra-uterine growth
restriction is obtained through pharmacological (streptozotocin), dietary (global food …

[PDF][PDF] Consequences of intra-uterine growth retardation for postnatal growth, metabolism and pathophysiology

PL Greenwood, AW Bell - REPRODUCTION-CAMBRIDGE …, 2003 - biosciproceedings.org
Intra-uterine growth retardation(IUGR), caused by maternal undernutrition or placental
insufficiency, is usually associated with disproportionately large reductions in the growth of …

[PDF][PDF] Fetal growth restriction: adaptations and consequences

IC McMillen, MB Adams, JT Ross… - REPRODUCTION …, 2001 - researchgate.net
A range of pathophysiological factors can result in a perturbation or restriction of fetal
growth, and the cardiovascular, neuroendocrine and metabolic adaptations of the fetus to …

[HTML][HTML] Placental insufficiency and fetal growth restriction lead to postnatal hypotension and altered postnatal growth in sheep

S Louey, ML Cock, KM Stevenson, R Harding - Pediatric research, 2000 - nature.com
Low birth weight has been associated with elevated arterial pressure in later life but
mechanisms are unknown. Our aim was to determine the effects of low birth weight resulting …

Aetiology and pathogenesis of IUGR

S Sankaran, PM Kyle - Best practice & research Clinical obstetrics & …, 2009 - Elsevier
Intrauterine growth restriction (IUGR) is a major cause of perinatal mortality and morbidity. A
complex and dynamic interaction of maternal, placental and fetal environment is involved in …