The ocular tissue microenvironment is immune privileged and uses several mechanisms of
immunosuppression to prevent the induction of inflammation. Besides being a blood-barrier …

The ocular tissue microenvironment is immune-privileged and uses multiple
immunosuppressive mechanisms to prevent the induction of inflammation. The retinal …

Immune reactivity in the retina can be critically important in inflammation and infections, but
regulation of this response is essential. The retinal pigment epithelial (RPE), a unique retinal …

Vision is dependent on proper function of several intraocular structures. Immune responses
to eliminate invading pathogens from the eye may threat vision by causing damage to these …

The RPE cell plays a pivotal role in retinal immunity. In fact, the RPE cell orchestrates both
innate and adaptive immunity and contains a plethora of factors to regulate the immune …

Purpose: We have previously found that retinal pigment epithelial (RPE) cells suppressed
endotoxin-stimulated macrophages; moreover, it induced expression of anti-inflammatory …

purpose. Retinal pigmented epithelial (RPE) cells may contribute to retinal immune
privilege. Daily phagocytosis and degradation of photoreceptor cell outer segment tips by …

The eye is an immune privileged tissue that insulates the visual system from local and
systemic immune provocation to preserve homeostatic functions of highly specialized retinal …

Innate immune cells such as neutrophils, monocyte-macrophages and microglial cells are
pivotal for the health and disease of the retina. For the maintenance of retinal homeostasis …

The ocular microenvironment is both immunosuppressive and anti-inflammatory in nature.
Pigment epithelial (PE) cells isolated from the eye possess the ability to suppress the T cell …