For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Sepsis is a life-threatening organ dysfunction that results from the body's response to
infection. It requires prompt recognition, appropriate antibiotics, careful hemodynamic …

Sepsis has been around since the dawn of time, having been described for more than 2000
years, although clinical definitions are recent. The consensus sepsis definitions have …

As of 2017, the World Health Organization has made the recognition, prevention, and
management of sepsis a global health priority. 1 Hippocrates considered the term a …

Over the past 30 years, 2 major factors have led to a perceived need for better definitions. In
particular, the increasing sophistication, at least in high-income countries, of modalities …

Sepsis is a clinical syndrome that results from the dysregulated inflammatory response to
infection that leads to organ dysfunction. The resulting losses to society in terms of financial …

Sepsis is among the oldest themes in medicine; however, despite modern advances, it
remains a leading cause of death in the United States. Every clinician should be able to …

Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the
disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving …

Sepsis is a common condition with high morbidity and mortality. Although many patients may
require critical care, this article considers the features of sepsis that are of most relevance to …

Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection,
and it probably represents a pattern of response by the immune system to injury. A hyper …