The construction of tissue-engineered devices for medical applications is now possible in
vitro using cell culture and bioreactors. Although methods of incorporating them back into …

The ability to create thick tissues is a major tissue engineering challenge, requiring the
development of a suitable vascular supply. Current trends are seeing the utilization of cells …

Vascularization is one of the great challenges that tissue engineering faces in order to
achieve sizeable tissue and organ substitutes that contain living cells. There are instances …

Current clinical treatment strategies for the bypassing of small diameter (< 6 mm) blood
vessels in the management of cardiovascular disease frequently fail due to a lack of suitable …

Background Tissue engineering techniques have been employed successfully in the
management of wounds, burns and cartilage repair. Current prosthetic alternatives to …

Initial take, development, and function of transplanted engineered tissue substitutes are
crucially dependent on rapid and adequate blood perfusion. Therefore, the development of …

The ultimate survival of tissue-engineered constructs in vivo depends on the provision of an
adequate blood supply to the engineered tissue and the capacity of the engineered …

The survival of engineered tissue constructs during the initial phase after their implantation
depends on the rapid development of an adequate vascularization. This, in turn, is a major …

Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

Long-term function of three-dimensional (3D) tissue constructs depends on adequate
vascularization after implantation. Accordingly, research in tissue engineering has focused …