[HTML][HTML] Metallothionein 1: A new spotlight on inflammatory diseases

H Dai, L Wang, L Li, Z Huang, L Ye - Frontiers in immunology, 2021 - frontiersin.org
MT1 has been demonstrated to be an essential stress protein in maintaining physiological
balance and regulating immune homeostasis. While the immunological involvement of MT1 …

[HTML][HTML] Metallothioneins: emerging modulators in immunity and infection

K Subramanian Vignesh, GS Deepe Jr - International journal of molecular …, 2017 - mdpi.com
Metallothioneins (MTs) are a family of metal-binding proteins virtually expressed in all
organisms including prokaryotes, lower eukaryotes, invertebrates and mammals. These …

[HTML][HTML] Mammalian metallothionein-2A and oxidative stress

XB Ling, HW Wei, J Wang, YQ Kong, YY Wu… - International journal of …, 2016 - mdpi.com
Mammalian metallothionein-2A (MT2A) has received considerable attention in recent years
due to its crucial pathophysiological role in anti-oxidant, anti-apoptosis, detoxification and …

Metallothionein as an anti‐inflammatory mediator

K Inoue, H Takano, A Shimada… - Mediators of …, 2009 - Wiley Online Library
The integration of knowledge concerning the regulation of MT, a highly conserved, low
molecular weight, cystein‐rich metalloprotein, on its proposed functions is necessary to …

Metallothionein functions and structural characteristics

E Carpene, G Andreani, G Isani - Journal of trace elements in medicine and …, 2007 - Elsevier
Metallothioneins (MTs) are low molecular weight proteins characterized by a high cysteine
content and give rise to metal-thiolate clusters. Most MTs have two metal clusters containing …

[HTML][HTML] A review of metallothionein isoforms and their role in pathophysiology

N Thirumoorthy, A Shyam Sunder… - World journal of surgical …, 2011 - Springer
The Metallothionein (MT) is a protein which has several interesting biological effects and
has been demonstrated increase focus on the role of MT in various biological systems in the …

[HTML][HTML] Metallothionein-3 as a multifunctional player in the control of cellular processes and diseases

JY Koh, SJ Lee - Molecular brain, 2020 - Springer
Transition metals, such as iron, copper, and zinc, play a very important role in life as the
regulators of various physiochemical reactions in cells. Abnormal distribution and …

[HTML][HTML] Mammalian metallothionein-3: New functional and structural insights

M Vašák, G Meloni - International journal of molecular sciences, 2017 - mdpi.com
Metallothionein-3 (MT-3), a member of the mammalian metallothionein (MT) family, is mainly
expressed in the central nervous system (CNS). MT-3 possesses a unique neuronal growth …

Advances in metallothionein structure and functions

M Vašák - Journal of Trace Elements in Medicine and Biology, 2005 - Elsevier
Metallothioneins (MTs) are a class of ubiquitously occurring low molecular weight cysteine-
and metal-rich proteins containing sulfur-based metal clusters. The conservation of these …

The physiological roles of extracellular metallothionein

MA Lynes, K Zaffuto, DW Unfricht… - Experimental …, 2006 - journals.sagepub.com
Metallothionein (MT) is a low-molecular-weight protein with a number of roles to play in
cellular homeostasis. MT is synthesized as a consequence of a variety of cellular stressors …