The Small Protein YmoA Controls the Csr System and Adjusts Expression of Virulence-Relevant Traits of Yersinia pseudotuberculosis

K Böhme, AK Heroven, S Lobedann, Y Guo… - Frontiers in …, 2021 - frontiersin.org
Virulence gene expression of Yersinia pseudotuberculosis changes during the different
stages of infection and this is tightly controlled by environmental cues. In this study, we show …

A direct link between the global regulator PhoP and the Csr regulon in Y. pseudotuberculosis through the small regulatory RNA CsrC

AM Nuss, F Schuster, A Kathrin Heroven, W Heine… - RNA biology, 2014 - Taylor & Francis
In this study we investigated the influence of the global response regulator PhoP on the
complex regulatory cascade controlling expression of early stage virulence genes of …

Transcriptomic Profiling of Yersinia pseudotuberculosis Reveals Reprogramming of the Crp Regulon by Temperature and Uncovers Crp as a Master Regulator of …

AM Nuss, AK Heroven, B Waldmann… - PLoS …, 2015 - journals.plos.org
One hallmark of pathogenic yersiniae is their ability to rapidly adjust their life-style and
pathogenesis upon host entry. In order to capture the range, magnitude and complexity of …

Genome-wide analysis of small RNAs expressed by Yersinia pestis identifies a regulator of the Yop-Ysc type III secretion system

CA Schiano, JT Koo, MJ Schipma… - Journal of …, 2014 - Am Soc Microbiol
Small noncoding RNA (sRNA) molecules are integral components of the regulatory
machinery for many bacterial species and are known to posttranscriptionally regulate …

YopN is required for efficient effector translocation and virulence in Yersinia pseudotuberculosis

S Bamyaci, S Ekestubbe, R Nordfelth… - Infection and …, 2018 - Am Soc Microbiol
Type III secretion systems (T3SSs) are used by various Gram-negative pathogens to subvert
the host defense by a host cell contact-dependent mechanism to secrete and translocate …

Identification of specific sequence motif of YopN of Yersinia pseudotuberculosis required for systemic infection

S Bamyaci, R Nordfelth, Å Forsberg - Virulence, 2019 - Taylor & Francis
Type III secretion systems (T3SSs) are tightly regulated key virulence mechanisms shared
by many Gram-negative pathogens. YopN, one of the substrates, is also crucial in regulation …

Regulation of Virulence Gene Expression by Regulatory RNA Elements in Yersinia pseudotuberculosis

AK Heroven, K Böhme, P Dersch - Advances in Yersinia Research, 2012 - Springer
The enteropathogenic bacterium Yersinia pseudotuberculosis produces different sets of
virulence factors that guarantee efficient colonization during the early stages, and …

The Small RNA Chaperone Hfq Is Required for the Virulence of Yersinia pseudotuberculosis

CA Schiano, LE Bellows, WW Lathem - Infection and immunity, 2010 - Am Soc Microbiol
Bacterial small, noncoding RNAs (sRNAs) participate in the posttranscriptional regulation of
gene expression, often by affecting protein translation, transcript stability, and/or protein …

Role of YopK in Yersinia pseudotuberculosis resistance against polymorphonuclear leukocyte defense

SE Thorslund, D Ermert, A Fahlgren… - Infection and …, 2013 - Am Soc Microbiol
The enteropathogen Yersinia pseudotuberculosis can survive in the harsh environment of
lymphoid compartments that abounds in immune cells. This capacity is dependent on the …

Loss of CNFY toxin-induced inflammation drives Yersinia pseudotuberculosis into persistency

W Heine, M Beckstette, AK Heroven, S Thiemann… - PLoS …, 2018 - journals.plos.org
Gastrointestinal infections caused by enteric yersiniae can become persistent and
complicated by relapsing enteritis and severe autoimmune disorders. To establish a …