Anti-CMV therapy, what next? A systematic review

C Gourin, S Alain, S Hantz - Frontiers in Microbiology, 2023 - frontiersin.org
Human cytomegalovirus (HCMV) is one of the main causes of serious complications in
immunocompromised patients and after congenital infection. There are currently drugs …

Maribavir, brincidofovir and letermovir: Efficacy and safety of new antiviral drugs for treating cytomegalovirus infections

P Frange, M Leruez-Ville - Medecine et maladies infectieuses, 2018 - Elsevier
Cytomegalovirus (CMV) infection is a common complication in immunocompromised
patients, especially after hematopoietic stem cell or solid organ transplantation. Therapeutic …

Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir

J Piret, G Boivin - Infectious Disease Reports, 2024 - mdpi.com
Cytomegalovirus (CMV) infections may increase morbidity and mortality in
immunocompromised patients. Until recently, standard antiviral drugs against CMV were …

Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance

J Piret, G Boivin - Antiviral research, 2019 - Elsevier
The prevention and treatment of human cytomegalovirus (HCMV) infections is based on the
use of antiviral agents that currently target the viral DNA polymerase and that may cause …

Safety considerations with current and emerging antiviral therapies for cytomegalovirus infection in transplantation

G El Helou, RR Razonable - Expert opinion on drug safety, 2019 - Taylor & Francis
Introduction: Human cytomegalovirus (HCMV) is a major contributor of morbidity and
mortality, and its management is essential for the successful outcome of solid organ and …

Antiviral treatment of cytomegalovirus infection: an update

G Härter, D Michel - Expert opinion on pharmacotherapy, 2012 - Taylor & Francis
This editorial summarizes recent developments in the management of ganciclovir-resistant
human cytomegalovirus (HCMV) infections. All current drugs available for systemic …

Evaluating the Safety of Maribavir for the Treatment of Cytomegalovirus

RG Gandhi, CN Kotton - Therapeutics and Clinical Risk …, 2022 - Taylor & Francis
Purpose of Review Cytomegalovirus (CMV) infections are a common complication in solid
organ (SOT) and hematopoietic stem cell transplant (HSCT) recipients, leading to increased …

Letermovir for the prevention of cytomegalovirus infection in adult cytomegalovirus-seropositive hematopoietic stem cell transplant recipients

F Foolad, SL Aitken, RF Chemaly - Expert review of clinical …, 2018 - Taylor & Francis
Introduction: Allogeneic hematopoietic cell transplants (allo-HCT) recipients are at the high-
risk of reactivation of cytomegalovirus (CMV), and reactivation is associated with significant …

Novel therapies for cytomegalovirus disease

C Steininger - Recent patents on anti-infective drug discovery, 2007 - ingentaconnect.com
Cytomegalovirus (CMV) infection is one of the most important infectious complications of
solid-organ transplantation, a serious, life-threatining, opportunistic pathogen in HIV-infected …

Challenges, recent advances and perspectives in the treatment of human cytomegalovirus infections

SJ Chen, SC Wang, YC Chen - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is ubiquitous worldwide and elicits global health problems.
The diseases associated with HCMV are a serious threat to humans, especially for the sick …