[HTML][HTML] miRNA-200b signature in the prevention of skin cancer stem cells by polyphenol-enriched blueberry preparation

N Alsadi, JF Mallet, C Matar - Journal of cancer prevention, 2021 - ncbi.nlm.nih.gov
Exposure of the skin to solar UV radiation leads to inflammation, DNA damage, and
dysregulation of cellular signaling pathways, which may cause skin cancer …

Role of a Polyphenol-Enriched Blueberry Preparation on Inhibition of Melanoma Cancer Stem Cells and Modulation of MicroRNAs

N Alsadi, N Yahfoufi, C Nessim, C Matar - Biomedicines, 2024 - mdpi.com
Melanoma is a type of skin cancer known for its high mortality rate. Cancer stem cells
(CSCs) are a subpopulation of cancer cells that significantly contribute to tumour recurrence …

Polyphenol-enriched blueberry preparation controls breast cancer stem cells by targeting FOXO1 and miR-145

JF Mallet, R Shahbazi, N Alsadi, C Matar - Molecules, 2021 - mdpi.com
Scientific evidence supports the early deregulation of epigenetic profiles during breast
carcinogenesis. Research shows that cellular transformation, carcinogenesis, and stemness …

Role of a polyphenol-enriched preparation on chemoprevention of mammary carcinoma through cancer stem cells and inflammatory pathways modulation

T Vuong, JF Mallet, M Ouzounova, S Rahbar… - Journal of Translational …, 2016 - Springer
Background Naturally occurring polyphenolic compounds from fruits, particularly from
blueberries, have been reported to be significantly involved in cancer chemoprevention and …

Role of a mixture of polyphenol compounds released after blueberry fermentation in chemoprevention of mammary carcinoma: In vivo involvement of miR-145

JF Mallet, R Shahbazi, N Alsadi, A Saleem… - International Journal of …, 2023 - mdpi.com
Epigenetic mechanisms such as microRNA (miRNA) deregulation seem to exert a central
role in breast cancer initiation and progression. Therefore, targeting epigenetics …

Regular Intake of green tea polyphenols suppresses the development of nonmelanoma skin cancer through miR-29-mediated epigenetic modifications

V Kansal, A Agarwal, A Harbour, H Farooqi… - Journal of Clinical …, 2022 - mdpi.com
Previously, we and others have shown that the regular intake of green tea polyphenols
(GTPs) reduces ultraviolet B (UVB) radiation-induced skin cancer by targeting multiple …

Involvement of microRNAs in epigallocatechin gallate-mediated UVB protection in human dermal fibroblasts

IS An, S An, S Park, SN Lee, S Bae - Oncology reports, 2013 - spandidos-publications.com
The green tea polyphenol epigallocatechin-3-gallate (EGCG) is a potent anti-oxidant and
anticancer compound. Recently, EGCG-mediated UVB photoprotection was reported in …

Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model

N Alsadi, H Yasavoli-Sharahi, R Mueller, C Cuenin… - Antioxidants, 2023 - mdpi.com
UVB significantly impacts the occurrence of cutaneous disorders, ranging from inflammatory
to neoplastic diseases. Polyphenols derived from plants have been found to exhibit …

Mechanisms underlying the protective effects of blueberry extract against ultraviolet radiation in a skin cell co-culture system

H Wang, J Liu, D Pang, T Li, RH Liu - Journal of Functional Foods, 2019 - Elsevier
Ultraviolet radiation induces skin damage, inflammation, and aging. To explore the
protective effects of blueberry extract (BE) against ultraviolet-C (UV-C) radiation, we …

Lemon balm extract (Melissa officinalis, L.) promotes melanogenesis and prevents UVB-induced oxidative stress and DNA damage in a skin cell model

A Pérez-Sánchez, E Barrajón-Catalán… - Journal of …, 2016 - Elsevier
Background Solar ultraviolet (UV) radiation is one of the main causes of a variety of
cutaneous disorders, including photoaging and skin cancer. Its UVB component (280–315 …