The bi-directional communication between the oocyte and its companion cumulus cells
(CCs) is crucial for development and functions of both cell types. Transcripts that are …

The growth and development of oocyte affect the functional activities of the surrounding
somatic cells. These cells are regulated by various types of hormones, proteins, metabolites …

Background Oocytes are the female gametes which establish the program of life after
fertilization. Interactions between oocyte and the surrounding cumulus cells at germinal …

Studying cumulus cell (CC) transcriptome is of great interest as it could provide a
noninvasive method to assess oocyte quality. In cattle, the search for quality markers has not …

Background Cumulus cells (CC) encapsulate growing oocytes and support their growth and
development. Transcriptomic signatures of CC have the potential to serve as valuable non …

In vitro maturation (IVM) of immature oocytes is widely used in assisted reproduction
technologies in cattle, and is increasingly used to treat human infertility. The development …

It is widely recognized that bi-directional communication exists between the human oocyte
and cumulus cells (CCs) which is essential for the production of competent oocytes. CCs …

Background Without intensive selection, the majority of bovine oocytes submitted to in vitro
embryo production (IVP) fail to develop to the blastocyst stage. This is attributed partly to …

Follicle size is recognized as a predictor of the potential for the enclosed oocyte to yield an
embryo following in vitro maturation and in vitro fertilization. Oocytes from larger follicles are …

Background Growing oocytes acquire the ability to mature through two-way communication
between gametes and surrounding somatic cumulus cells (CCs). Granulosa cells (GCs) …