The deeper understanding of metastasis phenomenon and detection of drug targets could
be a potential approach to minimize cancer mortality. In this study, attempts were taken to …

Over the past 10 years the serological analysis of recombinant cDNA expression libraries
(SEREX) has proved to be an effective method for the identification of tumour antigens. In …

The subcellular localization of a protein is closely linked to and indicates its function. The
metastatic tumor antigen (MTA) family has been under continuous investigation since its …

Purpose: Chromatin remodeling pathways are critical in the regulation of cancer-related
genes and are currently being explored as potential targets for therapeutic intervention. The …

The metastasis-associated (MTA) gene family is a critical component of the nucleosome
remodeling and histone deacetylase complex, and plays an important role in metastatic …

Background/Aim: c-Met (mesenchymal-epithelial transition factor) facilitates cancer
progression and is recognized as a promising drug target. The molecular target of gigantol …

Background: Metastasis is often derived from increased invasion and migration of tumor
cells, and is the most frequent cause of cancer-associated death. Either the prophylactic or …

Remarkably, majority of the cancer deaths are due to metastasis, not because of primary
tumors. Metastasis is one of the important hallmarks of cancer. During metastasis invasion of …

Abstract Metastatic tumor antigen 2 (MTA2) is a member of the MTA family that is closely
associated with tumor progression and metastasis. In this study, the expression profile of …

Cancer metastasis is a common biological phenomenon observed in malignant tumors that
can lead to death in affected individuals. Therefore, effective antimetastatic therapy and …