Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease: a systematic review and meta-analysis
X Ding, S Zhang, L Jiang, L Wang, T Li… - Translational …, 2021 - Springer
A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common
challenge for neurodegenerative diseases such as Alzheimer's disease (AD). Recent …
challenge for neurodegenerative diseases such as Alzheimer's disease (AD). Recent …
Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease …
Background There is still a substantial unmet need for less invasive and lower-cost blood-
based biomarkers to detect brain Alzheimer's disease (AD) pathology. This study is aimed to …
based biomarkers to detect brain Alzheimer's disease (AD) pathology. This study is aimed to …
Phosphorylated tau 181 serum levels predict Alzheimer's disease in the preclinical stage
W Qin, F Li, L Jia, Q Wang, Y Li, Y Wei, Y Li… - Frontiers in Aging …, 2022 - frontiersin.org
Background There is an urgent need for cost-effective, easy-to-measure biomarkers to
identify subjects who will develop Alzheimer's disease (AD), especially at the pre …
identify subjects who will develop Alzheimer's disease (AD), especially at the pre …
Differences between plasma and cerebrospinal fluid p-tau181 and p-tau231 in early Alzheimer's disease
A Pilotto, M Parigi, G Bonzi, B Battaglio… - Journal of …, 2022 - content.iospress.com
Plasma phosphorylated tau species have been recently proposed as peripheral markers of
Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects …
Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects …
Plasma tau proteins for the diagnosis of mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis
L Chen, X Niu, Y Wang, S Lv, X Zhou… - Frontiers in Aging …, 2022 - frontiersin.org
Objective Detecting plasma tau biomarkers used to be impossible due to their low
concentrations in blood samples. Currently, new high-sensitivity assays made it a reality. We …
concentrations in blood samples. Currently, new high-sensitivity assays made it a reality. We …
Development and validation of a high‐sensitivity assay for measuring p217+ tau in plasma
G Triana‐Baltzer, S Moughadam… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction Diagnosis of Alzheimer's disease (AD) based on amyloid beta (A),
pathologic tau (T), and neurodegeneration (N) biomarkers in peripheral fluids promises to …
pathologic tau (T), and neurodegeneration (N) biomarkers in peripheral fluids promises to …
Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease
JRF Santos, C Bauer, J Schuchhardt… - Journal of Neural …, 2019 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
presence of extracellular amyloid plaques (senile plaques) and intracellular neurofibrillary …
presence of extracellular amyloid plaques (senile plaques) and intracellular neurofibrillary …
Estimation of Tau and Phosphorylated Tau181 in Serum of Alzheimer's Disease and Mild Cognitive Impairment Patients
The elevated level of cerebrospinal fluid (CSF) Tau and phosphorylated Tau181 (p-Tau181)
proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p …
proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p …
[HTML][HTML] Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease
J Lantero-Rodriguez, G Salvadó, A Snellman… - Molecular …, 2024 - Springer
Background Novel phosphorylated-tau (p-tau) blood biomarkers (eg, p-tau181, p-tau217 or
p-tau231), are highly specific for Alzheimer's disease (AD), and can track amyloid-β (Aβ) and …
p-tau231), are highly specific for Alzheimer's disease (AD), and can track amyloid-β (Aβ) and …
Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology
The quantification of phosphorylated tau in biofluids, either cerebrospinal fluid (CSF) or
plasma, has shown great promise in detecting Alzheimer's disease (AD) pathophysiology …
plasma, has shown great promise in detecting Alzheimer's disease (AD) pathophysiology …
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