Colorectal cancer (CRC) results from the progressive accumulation of multiple genetic and
epigenetic aberrations within cells. The progression from colorectal adenoma to carcinoma …

Colorectal cancer is a heterogeneous disease. There are three main pathways to colorectal
cancer: the chromosomal instability pathway, the CpG island methylator phenotype pathway …

Originally, colorectal cancer (CRC) tumorigenesis was understood as a multistep process
that involved accumulation of tumor suppressor genes and oncogenes mutations, such as …

Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men globally. CRC arises from one or a combination of chromosomal instability …

Colorectal cancer (CRC) is a heterogeneous disease, developing through a multipathway
sequence of events guided by clonal selections. Pathways included in the development of …

Approximately 90% of colorectal cancer cases are sporadic without family history or genetic
predisposition, while in less than 10% a causative genetic event has been identified …

Colorectal cancer (CRC) is a heterogeneous disease, arising from many possible etiological
pathways. This heterogeneity can have important implications for CRC prognosis and …

Cancer is currently among the leading causes of mortality globally. Colorectal cancer (CRC)
ranks second among the most common types of cancer in terms of mortality worldwide. This …

Colorectal cancer (CRC) is the second most common newly diagnosed cancer and accounts
for the second highest number of cancer related deaths in Australia, the third worldwide and …

Colorectal cancer (CRC) is the third most commonly diagnosed cancer. This review gives an
overview of the current knowledge of molecular mechanisms of colorectal carcinogenesis …