NeuroPedia: neuropeptide database and spectral library

Y Kim, S Bark, V Hook, N Bandeira - Bioinformatics, 2011 - academic.oup.com
Neuropeptides are essential for cell–cell communication in neurological and endocrine
physiological processes in health and disease. While many neuropeptides have been …

HyPep: An open-source software for identification and discovery of neuropeptides using sequence homology search

NQ Vu, HC Yen, L Fields, W Cao… - Journal of proteome …, 2023 - ACS Publications
Neuropeptides are a class of endogenous peptides that have key regulatory roles in
biochemical, physiological, and behavioral processes. Mass spectrometry analyses of …

Neuropeptidomics: mass spectrometry-based qualitative and quantitative analysis

P Yin, X Hou, EV Romanova, JV Sweedler - Neuropeptides: methods and …, 2011 - Springer
Neuropeptidomics refers to a global characterization approach for the investigation of
neuropeptides, often under specific physiological conditions. Neuropeptides comprise a …

Peptidomics-based discovery of novel neuropeptides

M Svensson, K Sköld, P Svenningsson… - Journal of proteome …, 2003 - ACS Publications
Modern proteomic methodologies have significantly improved the possibilities of large-scale
identification of proteins. However, these methodologies are limited by their inability to …

[HTML][HTML] Neuropeptidomics: mass spectrometry-based identification and quantitation of neuropeptides

JE Lee - Genomics & informatics, 2016 - ncbi.nlm.nih.gov
Neuropeptides produced from prohormones by selective action of endopeptidases are vital
signaling molecules, playing a critical role in a variety of physiological processes, such as …

NeuroPep: a comprehensive resource of neuropeptides

Y Wang, M Wang, S Yin, R Jang, J Wang, Z Xue… - Database, 2015 - academic.oup.com
Neuropeptides play a variety of roles in many physiological processes and serve as
potential therapeutic targets for the treatment of some nervous-system disorders. In recent …

Evaluation of database search programs for accurate detection of neuropeptides in tandem mass spectrometry experiments

MN Akhtar, BR Southey, PE Andrén… - Journal of Proteome …, 2012 - ACS Publications
Neuropeptide identification in mass spectrometry experiments using database search
programs developed for proteins is challenging. Unlike proteins, the detection of the …

Recent advances in mass spectrometry analysis of neuropeptides

A Phetsanthad, NQ Vu, Q Yu… - Mass spectrometry …, 2023 - Wiley Online Library
Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Advances in mass spectrometric tools for probing neuropeptides

A Buchberger, Q Yu, L Li - Annual review of analytical chemistry, 2015 - annualreviews.org
Neuropeptides are important mediators in the functionality of the brain and other
neurological organs. Because neuropeptides exist in a wide range of concentrations …

Diversity of neuropeptide cell-cell signaling molecules generated by proteolytic processing revealed by neuropeptidomics mass spectrometry

V Hook, CB Lietz, S Podvin, T Cajka… - Journal of the American …, 2018 - ACS Publications
Neuropeptides are short peptides in the range of 3–40 residues that are secreted for cell-cell
communication in neuroendocrine systems. In the nervous system, neuropeptides comprise …