Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Microenvironment imbalance of spinal cord injury

B Fan, Z Wei, X Yao, G Shi, X Cheng… - Cell …, 2018 - journals.sagepub.com
Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient
physiology and psychology. The microenvironment of the injured spinal cord is complicated …

[HTML][HTML] Spinal cord injury and related clinical trials

YH Kim, KY Ha, SI Kim - Clinics in orthopedic surgery, 2017 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) has been considered an incurable condition and it often causes
devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: The development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …

Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and Targeted Therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Pathophysiology and therapeutic approaches for spinal cord injury

R Lima, A Monteiro, AJ Salgado, S Monteiro… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Strategies and prospects of effective neural circuits reconstruction after spinal cord injury

B Yang, F Zhang, F Cheng, L Ying, C Wang, K Shi… - Cell Death & …, 2020 - nature.com
Due to the disconnection of surviving neural elements after spinal cord injury (SCI), such
patients had to suffer irreversible loss of motor or sensory function, and thereafter enormous …