Exclusively neuron-centric approaches to neuropathological mechanisms have not resulted
in major new breakthroughs in the prevention and therapy of neurodegenerative diseases …

Neuroglia is critically important for controlling the brain homeostasis and for mounting the
brain defence against pathological insults. Here, we overview recent data about the role of …

Neuroglial cells are fundamental for control of brain homeostasis and they represent the
intrinsic brain defence system. All forms in neuropathology therefore inevitably involve glia …

The main pathological feature of the neurodegenerative diseases is represented by
neuronal death that represents the final step of a cascade of adverse/hostile events. Early in …

Presenting the latest research in glial cell function gleaned from new techniques in imaging
and molecular biology, this second edition covers multiple aspects of glial cells, including …

In injury and disease, microglia and astrocytes-two major non-neuronal cell types in the
central nervous system (CNS)-undergo morphological, transcriptional, and functional …

Chronic neurodegenerative diseases represent major unmet needs for therapeutic
interventions. Recently, the neurocentric view of brain function and disease has been …

The complexity of neuronal networks cannot only be explained by neuronal activity so
neurobiological research in the last decade has focused on different components of the …

Astrocytes play key roles in CNS development as well as well as neuro-supportive roles in
the mature brain including ionic, bioenergetic and redox homeostasis. Astrocytes undergo …

Growing evidence indicates that astrocytes cannot be just considered as passive supportive
cells deputed to preserve neuronal activity and survival, but rather they are involved in a …