[HTML][HTML] Gene interfered-ferroptosis therapy for cancers

J Gao, T Luo, J Wang - Nature communications, 2021 - nature.com
Although some effective therapies have been available for cancer, it still poses a great threat
to human health and life due to its drug resistance and low response in patients. Here, we …

Nanomedicine targeting ferroptosis to overcome anticancer therapeutic resistance

J Cai, X Xu, PE Saw - Science China Life Sciences, 2024 - Springer
A potential reason for the failure of tumor therapies is treatment resistance. Resistance to
chemotherapy, radiotherapy, and immunotherapy continues to be a major obstacle in clinic …

[HTML][HTML] Novel iron oxide nanoparticles induce ferroptosis in a panel of cancer cell lines

R Fernández-Acosta, C Iriarte-Mesa… - Molecules, 2022 - mdpi.com
The use of nanomaterials rationally engineered to treat cancer is a burgeoning field that has
reported great medical achievements. Iron-based polymeric nano-formulations with …

[HTML][HTML] Targeting ferroptosis to iron out cancer

B Hassannia, P Vandenabeele, TV Berghe - Cancer cell, 2019 - cell.com
One of the key challenges in cancer research is how to effectively kill cancer cells while
leaving the healthy cells intact. Cancer cells often have defects in cell death executioner …

[HTML][HTML] Iron and magnetic: new research direction of the ferroptosis-based cancer therapy

S Wang, J Luo, Z Zhang, D Dong, Y Shen… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Ferroptosis is an iron depend cell death which caused by lipid peroxidation. Abnormal iron
metabolism and high intracellular iron content are the characteristics of most cancer cells …

The potential application of nanomaterials for ferroptosis-based cancer therapy

Y Li, X Wei, F Tao, C Deng, C Lv, C Chen… - Biomedical …, 2021 - iopscience.iop.org
Ferroptosis is a new type of programmed cell death, which is expected to become an
important strategy of cancer treatment. Traditional strategies for inducing iron death are …

Recent advancements in nanomaterial-mediated ferroptosis-induced cancer therapy: Importance of molecular dynamics and novel strategies

N Dhas, R Kudarha, R Tiwari, G Tiwari, N Garg… - Life Sciences, 2024 - Elsevier
Ferroptosis is a novel type of controlled cell death resulting from an imbalance between
oxidative harm and protective mechanisms, demonstrating significant potential in combating …

[HTML][HTML] Induction of ferroptosis using functionalized iron-based nanoparticles for anti-cancer therapy

C Bae, H Kim, YM Kook, C Lee, C Kim, C Yang… - Materials Today Bio, 2022 - Elsevier
Ferroptosis, a cell death pathway that is induced in response to iron, has recently attracted
remarkable attention given its emerging therapeutic potential in cancer cells. The need for a …

[HTML][HTML] Ferroptosis-inducing nanomedicine for cancer therapy

Y Wang, T Liu, X Li, H Sheng, X Ma… - Frontiers in Pharmacology, 2021 - frontiersin.org
Ferroptosis, a new iron-and reactive oxygen species–dependent form of regulated cell
death, has attracted much attention in the therapy of various types of tumors. With the …

[HTML][HTML] Ferroptosis assassinates tumor

T Luo, Y Wang, J Wang - Journal of Nanobiotechnology, 2022 - Springer
In 2020, nearly 20 million peoples got cancer and nearly 10 million peoples died of cancer,
indicating the cancer remains a great threat to human health and life. New therapies are still …