Two‐Pronged Intracellular Co‐Delivery of Antigen and Adjuvant for Synergistic Cancer Immunotherapy
J Meng, P Zhang, Q Chen, Z Wang, Y Gu… - Advanced …, 2022 - Wiley Online Library
Nanovaccines have emerged as promising alternatives or complements to conventional
cancer treatments. Despite the progresses, specific co‐delivery of antigen and adjuvant to …
cancer treatments. Despite the progresses, specific co‐delivery of antigen and adjuvant to …
Targeted codelivery of an antigen and dual agonists by hybrid nanoparticles for enhanced cancer immunotherapy
L Zhang, S Wu, Y Qin, F Fan, Z Zhang, C Huang… - Nano …, 2019 - ACS Publications
Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine
based on nanotechnology could be a promising way to efficiently induce potent immune …
based on nanotechnology could be a promising way to efficiently induce potent immune …
Engineering ApoE3-incorporated biomimetic nanoparticle for efficient vaccine delivery to dendritic cells via macropinocytosis to enhance cancer immunotherapy
S Zhou, Y Huang, Y Chen, S Liu, M Xu, T Jiang… - Biomaterials, 2020 - Elsevier
Efficient delivery of vaccines to dendritic cells (DCs) is critical for inducing sufficient immune
response and realizing effective cancer immunotherapy. In the past decade, researchers …
response and realizing effective cancer immunotherapy. In the past decade, researchers …
Amplified cancer immunotherapy of a surface-engineered antigenic microparticle vaccine by synergistically modulating tumor microenvironment
H Zhao, B Zhao, L Wu, H Xiao, K Ding, C Zheng… - ACS …, 2019 - ACS Publications
Efficient cancer vaccines not only require the co-delivery of potent antigens and highly
immunostimulatory adjuvants to initiate robust tumor-specific host immune response but also …
immunostimulatory adjuvants to initiate robust tumor-specific host immune response but also …
A visible codelivery nanovaccine of antigen and adjuvant with self-carrier for cancer immunotherapy
X Dong, J Liang, A Yang, Z Qian… - ACS applied materials …, 2019 - ACS Publications
Codelivery nanovaccines of antigens and adjuvants have achieved positive therapy for
cancer immunotherapy. The insufficient immunogenicity of these vaccines leads to the …
cancer immunotherapy. The insufficient immunogenicity of these vaccines leads to the …
Hybrid nanovaccine for the co-delivery of the mRNA antigen and adjuvant
J Yang, S Arya, P Lung, Q Lin, J Huang, Q Li - Nanoscale, 2019 - pubs.rsc.org
For efficient cancer vaccines, the antitumor function largely relies on cytotoxic T cells, whose
activation can be effectively induced via antigen-encoding mRNA, making mRNA-based …
activation can be effectively induced via antigen-encoding mRNA, making mRNA-based …
Cancer cell membrane-coated adjuvant nanoparticles with mannose modification for effective anticancer vaccination
Tumor vaccines for cancer prevention and treatment have attracted tremendous interests in
the area of cancer immunotherapy in recent years. In this work, we present a strategy to …
the area of cancer immunotherapy in recent years. In this work, we present a strategy to …
Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger
The antitumor efficacy of tumor vaccines is often limited by weak T cell responses and poor
activated T cells infiltration. Herein, we reported a novel synergistic strategy to …
activated T cells infiltration. Herein, we reported a novel synergistic strategy to …
Orchestrated yolk–shell nanohybrids regulate macrophage polarization and dendritic cell maturation for oncotherapy with augmented antitumor immunity
The protumoral and immunosuppressive tumor microenvironments greatly limit the antitumor
immune responses of nanoparticles for cancer immunotherapy. Here, the intrinsic …
immune responses of nanoparticles for cancer immunotherapy. Here, the intrinsic …
Engineering anti-cancer nanovaccine based on antigen cross-presentation
Dendritic cells (DCs) present exogenous antigens on major histocompatibility complex
(MHC) class I molecules, thereby activating CD8+ T cells, contributing to tumor elimination …
(MHC) class I molecules, thereby activating CD8+ T cells, contributing to tumor elimination …
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