Hematopoietic SCT with cryopreserved grafts: adverse reactions after transplantation and cryoprotectant removal before infusion

Z Shu, S Heimfeld, D Gao - Bone marrow transplantation, 2014 - nature.com
Transplantation of hematopoietic stem cells (HSCs) has been successfully developed as a
part of treatment protocols for a large number of clinical indications, and cryopreservation of …

Cryopreservation of hematopoietic stem cells: emerging assays, cryoprotectant agents, and technology to improve outcomes

K Hornberger, G Yu, D McKenna, A Hubel - Transfusion Medicine and …, 2019 - karger.com
Hematopoietic stem cell (HSC) therapy is widely used to treat a growing number of
hematological and non-hematological diseases. Cryopreservation of HSCs allows for cells …

Historical perspectives and the future of adverse reactions associated with haemopoietic stem cells cryopreserved with dimethyl sulfoxide

MA Cox, J Kastrup, M Hrubiško - Cell and tissue banking, 2012 - Springer
A retrospective review of the published literature identified several hundred adverse
reactions (eg nausea, chills, cardiac arrhythmias, neurological symptoms and respiratory …

Cryopreservation of hematopoietic and non-hematopoietic stem cells

KK Fleming, A Hubel - Transfusion and Apheresis Science, 2006 - Elsevier
Recent studies illustrate the potential for improving the cryopreservation of stem cells.
Reduced DMSO concentrations in the cryopreservation medium, post thaw washing of cells …

Hematopoietic stem cell cryopreservation: a review of current techniques

SD ROWLEY - Journal of hematotherapy, 1992 - liebertpub.com
Hematopoietic stem cells (HSC) can be stored for prolonged periods at cryogenic
temperatures. The techniques currently used were derived from the initial report in 1949 of …

Improved post-thaw recovery of peripheral blood stem/progenitor cells using a novel intracellular-like cryopreservation solution

DM Clarke, DJ Yadock, IB Nicoud, AJ Mathew… - …, 2009 - Taylor & Francis
Background aims Peripheral blood stem cells (PBSC) have become the preferred stem cell
source for autologous hematopoietic transplantation. A critical aspect of this treatment …

Long-term hematologic reconstitution and clinical evaluation of autologous peripheral blood stem cell transplantation after cryopreservation of cells with 5% and 10 …

A Galmes, A Gutiérrez, A Sampol Mayol… - …, 2007 - docusalut.com
We report the long-term evaluation over 12 years of a simplified technique for stem-cell
cryopreservation at-80 degrees C without rate-controlled freezing and with 5%(n= 251) or …

Reduction of DMSO concentration in cryopreservation mixture from 10% to 7.5% and 5% has no impact on engraftment after autologous peripheral blood stem cell …

I Mitrus, A Smagur, W Fidyk, M Czech… - Bone Marrow …, 2018 - nature.com
The procedure of autologous peripheral blood stem cell transplantation (autoPBSCT)
requires cryopreservation of cells in a mixture containing dimethyl sulfoxide (DMSO). DMSO …

Cryopreservation of hematopoietic progenitor cells with 5‐percent dimethyl sulfoxide at− 80° C without rate‐controlled freezing

A Galmes, J Besalduch, J Bargay, N Matamoros… - …, 1996 - Wiley Online Library
Background: Cryopreservation of hematopoietic cells with the rate‐controlled method is
used in the majority of centers. In recent years, there has been a trend toward the …

Use of different DMSO concentrations for cryopreservation of autologous peripheral blood stem cell grafts does not have any major impact on levels of leukocyte-and …

ÇA Akkök, K Liseth, T Hervig, A Ryningen, Ø Bruserud… - Cytotherapy, 2009 - Elsevier
Background aims Infusion of stem cell autografts can be associated with adverse effects.
Necrotic normal leukocytes, cytokines or intracellular mediators released from leukocytes …