Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors

A Tuckfield, DR Clouston, TM Wilanowski… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract The Polycomb group (PcG) of proteins represses homeotic gene expression
through the assembly of multiprotein complexes on key regulatory elements. The …

[HTML][HTML] RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1

E García, C Marcos‐Gutiérrez, M del Mar Lorente… - The EMBO …, 1999 - embopress.org
The products of the Polycomb group (PcG) of genes are necessary for the maintenance of
transcriptional repression of a number of important developmental genes, including the …

Loss-and gain-of-function mutations show a polycomb group function for Ring1A in mice

MM Lorente, C Marcos-Gutiérrez, C Pérez… - …, 2000 - journals.biologists.com
The products of the Polycomb group (PcG) of genes act as transcriptional repressors
involved in the maintenance of homeotic gene expression patterns throughout development …

[HTML][HTML] The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins

N Gorfinkiel, L Fanti, T Melgar, E Garcıa… - Mechanisms of …, 2004 - Elsevier
In Drosophila, the Polycomb group (PcG) of genes is required for the maintenance of
homeotic gene repression during development. Here, we have characterized the Drosophila …

HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties

JI Bárdos, AJ Saurin, C Tissot, E Duprez… - Journal of Biological …, 2000 - ASBMB
Polycomb group (PcG) proteins were first described in Drosophila as factors responsible for
maintaining the transcriptionally repressed state of Hox/homeotic genes in a stable and …

RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor

DPE Satijn, MJ Gunster, J van der Vlag… - … and cellular biology, 1997 - Taylor & Francis
The Polycomb (Pc) protein is a component of a multimeric, chromatin-associated Polycomb
group (PcG) protein complex, which is involved in stable repression of gene activity. The …

The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors

SB Ting, T Wilanowski, L Cerruti, LL Zhao… - Biochemical …, 2003 - portlandpress.com
The Drosophila gene grainyhead is the founding member of a large family of genes
encoding developmental transcription factors that are highly conserved from fly to human …

Efficient and specific targeting of Polycomb group proteins requires cooperative interaction between Grainyhead and Pleiohomeotic

A Blastyák, RK Mishra, F Karch… - Molecular and cellular …, 2006 - Taylor & Francis
Specific targeting of the protein complexes formed by the Polycomb group of proteins is
critically required to maintain the inactive state of a group of developmentally regulated …

RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity

DPE Satijn, AP Otte - Molecular and cellular biology, 1999 - Taylor & Francis
Polycomb-group (PcG) proteins form large multimeric protein complexes that are involved in
maintaining the transcriptionally repressive state of genes. Previously, we reported that …

Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA

NM Mulholland, IFG King, RE Kingston - Genes & development, 2003 - genesdev.cshlp.org
Repression and activation of the expression of homeotic genes are maintained by proteins
encoded by the Polycomb group (PcG) and trithorax group (trxG) genes. Complexes formed …