Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors
A Tuckfield, DR Clouston, TM Wilanowski… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract The Polycomb group (PcG) of proteins represses homeotic gene expression
through the assembly of multiprotein complexes on key regulatory elements. The …
through the assembly of multiprotein complexes on key regulatory elements. The …
[HTML][HTML] RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1
E García, C Marcos‐Gutiérrez, M del Mar Lorente… - The EMBO …, 1999 - embopress.org
The products of the Polycomb group (PcG) of genes are necessary for the maintenance of
transcriptional repression of a number of important developmental genes, including the …
transcriptional repression of a number of important developmental genes, including the …
Loss-and gain-of-function mutations show a polycomb group function for Ring1A in mice
MM Lorente, C Marcos-Gutiérrez, C Pérez… - …, 2000 - journals.biologists.com
The products of the Polycomb group (PcG) of genes act as transcriptional repressors
involved in the maintenance of homeotic gene expression patterns throughout development …
involved in the maintenance of homeotic gene expression patterns throughout development …
[HTML][HTML] The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins
N Gorfinkiel, L Fanti, T Melgar, E Garcıa… - Mechanisms of …, 2004 - Elsevier
In Drosophila, the Polycomb group (PcG) of genes is required for the maintenance of
homeotic gene repression during development. Here, we have characterized the Drosophila …
homeotic gene repression during development. Here, we have characterized the Drosophila …
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties
Polycomb group (PcG) proteins were first described in Drosophila as factors responsible for
maintaining the transcriptionally repressed state of Hox/homeotic genes in a stable and …
maintaining the transcriptionally repressed state of Hox/homeotic genes in a stable and …
RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor
DPE Satijn, MJ Gunster, J van der Vlag… - … and cellular biology, 1997 - Taylor & Francis
The Polycomb (Pc) protein is a component of a multimeric, chromatin-associated Polycomb
group (PcG) protein complex, which is involved in stable repression of gene activity. The …
group (PcG) protein complex, which is involved in stable repression of gene activity. The …
The identification and characterization of human Sister-of-Mammalian Grainyhead (SOM) expands the grainyhead-like family of developmental transcription factors
SB Ting, T Wilanowski, L Cerruti, LL Zhao… - Biochemical …, 2003 - portlandpress.com
The Drosophila gene grainyhead is the founding member of a large family of genes
encoding developmental transcription factors that are highly conserved from fly to human …
encoding developmental transcription factors that are highly conserved from fly to human …
Efficient and specific targeting of Polycomb group proteins requires cooperative interaction between Grainyhead and Pleiohomeotic
Specific targeting of the protein complexes formed by the Polycomb group of proteins is
critically required to maintain the inactive state of a group of developmentally regulated …
critically required to maintain the inactive state of a group of developmentally regulated …
RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity
DPE Satijn, AP Otte - Molecular and cellular biology, 1999 - Taylor & Francis
Polycomb-group (PcG) proteins form large multimeric protein complexes that are involved in
maintaining the transcriptionally repressive state of genes. Previously, we reported that …
maintaining the transcriptionally repressive state of genes. Previously, we reported that …
Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA
NM Mulholland, IFG King, RE Kingston - Genes & development, 2003 - genesdev.cshlp.org
Repression and activation of the expression of homeotic genes are maintained by proteins
encoded by the Polycomb group (PcG) and trithorax group (trxG) genes. Complexes formed …
encoded by the Polycomb group (PcG) and trithorax group (trxG) genes. Complexes formed …