Combined effect of arsenic and polystyrene-nanoplastics at environmentally relevant concentrations in mice liver: activation of apoptosis, pyroptosis and excessive …

G Zhong, G Rao, L Tang, S Wu, Z Tang, R Huang… - Chemosphere, 2022 - Elsevier
The ecological risks caused by the coexistence of pollutants such as arsenic (As) and
polystyrene-nanoplastics (PSNPs) in the environment have become a non-negligible …

Arsenic or/and antimony induced mitophagy and apoptosis associated with metabolic abnormalities and oxidative stress in the liver of mice

G Zhong, F Wan, S Wu, X Jiang, Z Tang… - Science of the Total …, 2021 - Elsevier
Arsenic and antimony are coexisting cumulative environmental pollutants that cause severe
and extensive biological toxicity. However, their interactions and toxic mechanisms in the …

Exposure to Polystyrene nanoparticles induces liver damage in rat via induction of oxidative stress and hepatocyte apoptosis

NAE Yasin, ME El-Naggar, ZSO Ahmed… - Environmental …, 2022 - Elsevier
Plastic products are widely used in different applications. Thus, exposure of human and
other organisms to these products may affect their biological system. The current study was …

Polystyrene microplastics with different sizes induce the apoptosis and necroptosis in liver through the PTEN/PI3K/AKT/autophagy axis

S Wang, H Wu, X Shi, Y Wang, S Xu - Science of The Total Environment, 2023 - Elsevier
The production of plastics worldwide has been instrumental in the progress of modern
society, while the increasing accumulation of plastics castoff in oceans, soils and anywhere …

Activation of pyroptosis and ferroptosis is involved in the hepatotoxicity induced by polystyrene microplastics in mice

Y Mu, J Sun, Z Li, W Zhang, Z Liu, C Li, C Peng, G Cui… - Chemosphere, 2022 - Elsevier
Microplastics (MPs) are new environmental pollutants and have received widespread
attention in recent years, but the toxicity of the MPs remains to be fully elucidated. To explore …

ROS and DRP1 interactions accelerate the mitochondrial injury induced by polystyrene nanoplastics in human liver HepG2 cells

Y Li, M Guo, S Niu, M Shang, X Chang, Z Sun… - Chemico-Biological …, 2023 - Elsevier
Microplastics have become a serious environmental pollutant and subsequently have
harmful effects on human health. Thus, the impacts of microplastics on human cells need to …

Nanoplastics promote arsenic-induced ROS accumulation, mitochondrial damage and disturbances in neurotransmitter metabolism of zebrafish (Danio rerio)

C Zhang, Y Li, H Yu, L Ye, T Li, X Zhang… - Science of the Total …, 2023 - Elsevier
As a carrier, nanoplastics (NPs) can adsorb other toxic substances and thus modify their
biological toxicity. Numerous studies have investigated the neurotoxic of high concentrations …

[HTML][HTML] Nanoplastics aggravate the toxicity of arsenic to AGS cells by disrupting ABC transporter and cytoskeleton

P Lin, Y Guo, L He, X Liao, X Chen, L He, Z Lu… - Ecotoxicology and …, 2021 - Elsevier
The coexistence of nanoplastics (NPs) and pollutants such as arsenic (As) has become an
unignorable environmental problem. However, there is still a considerable knowledge gap …

Adverse effects and underlying mechanism of amorphous silica nanoparticles in liver

Q Liang, M Sun, Y Ma, F Wang, Z Sun, J Duan - Chemosphere, 2023 - Elsevier
Amorphous silica nanoparticles (SiNPs) have been widely used and mass-producted due to
its unique properties. With the life cycle of SiNPs-based products, SiNPs are further released …

Polystyrene micro (nano) plastics damage the organelles of RBL-2H3 cells and promote MOAP-1 to induce apoptosis

L Liu, B Liu, B Zhang, Y Ye, W Jiang - Journal of Hazardous Materials, 2022 - Elsevier
The ubiquity of microplastics increases the exposure risks and health threats to humans. In
this study, rat basophilic leukemia (RBL-2H3) cells were exposed to polystyrene particles …