Recent studies show improved outcomes in ambulated lung failure patients. Ambulation still
remains a challenge in these patients. This necessitates development of more compact and …

Background Conventional extracorporeal membrane oxygenation (ECMO) is cumbersome
and is associated with high morbidity and mortality. We are currently developing the …

BACKGROUND: The purpose of this study was to evaluate the long-term in-vivo
hemodynamics, gas transfer, and biocompatibility of an integrated artificial pump-lung (APL) …

Respiratory failure is a significant problem within the pediatric population. A means of
respiratory support that readily allows ambulation could improve treatment. The Pittsburgh …

Background. A wearable artificial lung could improve lung transplantation outcomes by
easing implementation of physical rehabilitation during long-term pretransplant respiratory …

BACKGROUND: Conventional extracorporeal membrane oxygenation is bulky and non-
ambulatory and requires multiple blood transfusions. We hypothesized that a percutaneous …

The purpose of this study was to assess the biocompatibility of a newly developed long‐term
wearable artificial pump‐lung (APL) in a clinically relevant ovine animal model. The …

BACKGROUND: To provide long-term ambulatory cardiopulmonary and respiratory support
for adult patients, a novel wearable artificial pump-lung device has been developed. The …

The scarcity of donor organs has led to the development of devices that provide optimal long‐
term respiratory or cardiopulmonary support to bridge recipients as they wait for lung and/or …

OBJECTIVES: Currently available therapies for acute and chronic lung diseases have not
been effective and have various problems associated with the technologies used. We …