[HTML][HTML] Recent progress in mucosal vaccine development: potential and limitations

N Lycke - Nature reviews immunology, 2012 - nature.com
Most pathogens access the body through the mucosal membranes. Therefore, effective
vaccines that protect at these sites are much needed. However, despite early success with …

Novel vaccine development strategies for inducing mucosal immunity

Y Fukuyama, D Tokuhara, K Kataoka… - Expert review of …, 2012 - Taylor & Francis
To develop protective immune responses against mucosal pathogens, the delivery route
and adjuvants for vaccination are important. The host, however, strives to maintain mucosal …

Challenges in mucosal vaccines for the control of infectious diseases

T Azegami, Y Yuki, H Kiyono - International immunology, 2014 - academic.oup.com
The mucosal surface is the largest route through which pathogens enter the human body. To
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …

Mucosal vaccines: Strategies and challenges

M Li, Y Wang, Y Sun, H Cui, SJ Zhu, HJ Qiu - Immunology letters, 2020 - Elsevier
Mucosal immunization has potential benefits over conventional parenteral immunization,
eliciting immune defense in both mucosal and systemic tissue for protecting from pathogen …

[HTML][HTML] Mucosal vaccines—fortifying the frontiers

EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

Recent advances in mucosal vaccine development

H Chen - Journal of controlled release, 2000 - Elsevier
Proper stimulation of the mucosal immune system is critical for the effective protection of
mucosal surfaces against colonization and invasion of infectious agents. This requires …

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

A Srivastava, DV Gowda, SRV Madhunapantula… - Apmis, 2015 - Wiley Online Library
Mucosal immune responses are the first‐line defensive mechanisms against a variety of
infections. Therefore, immunizations of mucosal surfaces from which majority of infectious …

Defending the mucosa: adjuvant and carrier formulations for mucosal immunity

LB Lawson, EB Norton, JD Clements - Current opinion in immunology, 2011 - Elsevier
A majority of infectious microorganisms either colonize or cross mucosal surfaces to enter
the host. A major goal in vaccine design is to induce a protective, lasting immune response …

New insights in mucosal vaccine development

V Pavot, N Rochereau, C Genin, B Verrier, S Paul - Vaccine, 2012 - Elsevier
Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures …

[HTML][HTML] Vaccines against mucosal infections

J Holmgren, AM Svennerholm - Current opinion in immunology, 2012 - Elsevier
There remains a great need to develop vaccines against many of the pathogens that infect
mucosal tissues or have a mucosal port of entry. Parenteral vaccination may protect in some …