Effects of collagen membranes and bone substitute differ in periodontal ligament cell microtissues and monolayers

K Janjić, H Agis, A Moritz, X Rausch‐Fan… - Journal of …, 2022 - Wiley Online Library
Background Barrier membranes and bone substitute are major tools of guided tissue
regeneration (GTR) after periodontal disease. Integrity of the periodontal ligament plays a …

Extracellular matrix derived from periodontal ligament cells maintains their stemness and enhances redifferentiation via the wnt pathway

JC Zhang, ZC Song, YR Xia… - Journal of Biomedical …, 2018 - Wiley Online Library
Large numbers of viable cells cannot be obtained from periodontal ligament tissues of
patients with periodontitis. Therefore, it is imperative to establish an ex vivo environment that …

Extracellular matrix membrane induces cementoblastic/osteogenic properties of human periodontal ligament stem cells

Y Wang, S Papagerakis, D Faulk, SF Badylak… - Frontiers in …, 2018 - frontiersin.org
Objective: Periodontitis affects nearly 90% of adults over the age of 70, resulting to
periodontal tissue infection, destruction, and ultimately tooth loss. Guided tissue …

Tissue‐specific composite cell aggregates drive periodontium tissue regeneration by reconstructing a regenerative microenvironment

B Zhu, W Liu, H Zhang, X Zhao, Y Duan… - Journal of Tissue …, 2017 - Wiley Online Library
Periodontitis is the most common cause of periodontium destruction. Regeneration of
damaged tissue is the expected treatment goal. However, the regeneration of a functional …

An immunohistochemical study of matrix molecules associated with barrier membrane‐mediated periodontal wound healing

S Ivanovski, H Li, T Daley… - Journal of periodontal …, 2000 - Wiley Online Library
Guided tissue regeneration (GTR) is a clinical procedure developed to facilitate periodontal
regeneration by using barrier membranes to selectively promote the repopulation of a …

Periodontal-derived mesenchymal cell sheets promote periodontal regeneration in inflammatory microenvironment

S Guo, J Kang, B Ji, W Guo, Y Ding, Y Wu… - … Engineering Part A, 2017 - liebertpub.com
In this study, we investigated the periodontal regenerative potential of dental follicle cell
(DFC) sheets and periodontal ligament cell (PDLC) sheets in the simulating inflammatory …

Extracellular matrix induces periodontal ligament reconstruction in vivo

N Nakamura, A Ito, T Kimura, A Kishida - International journal of …, 2019 - mdpi.com
One of the problems in dental implant treatment is the lack of periodontal ligament (PDL),
which supports teeth, prevents infection, and transduces sensations such as chewiness. The …

Decellularized human periodontal ligament for periodontium regeneration

H Son, M Jeon, HJ Choi, HS Lee, IH Kim, CM Kang… - PLoS …, 2019 - journals.plos.org
Regenerating the periodontal ligament (PDL) is a crucial factor for periodontal tissue
regeneration in the presence of traumatized and periodontally damaged teeth. Various …

Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

J Hatakeyama, Y Hatakeyama, I Takahashi… - Oral …, 2007 - Wiley Online Library
Objective: Hydroxiapatite (HA) has been suggested as a useful biomaterial to support the
regeneration of tissues. In this study, we investigated the adhesion of periodontal ligament …

Matrix control of periodontal ligament cell activity via synthetic hydrogel scaffolds

D Fraser, T Nguyen, DSW Benoit - Tissue Engineering Part A, 2021 - liebertpub.com
Rebuilding the tooth-supporting tissues (periodontium) destroyed by periodontitis remains a
clinical challenge. Periodontal ligament cells (PDLCs), multipotent cells within the …