Currents of memory: recent progress, translational challenges, and ethical considerations in fornix deep brain stimulation trials for Alzheimer's disease
The serendipitous discovery of triggered autobiographical memories and eventual memory
improvement in an obese patient who received fornix deep brain stimulation in 2008 paved …
improvement in an obese patient who received fornix deep brain stimulation in 2008 paved …
Deep brain stimulation of fornix for memory improvement in Alzheimer's disease: A critical review
R Li, C Zhang, Y Rao, TF Yuan - Ageing research reviews, 2022 - Elsevier
Memory reflects the brain function in encoding, storage and retrieval of the data or
information, which is a fundamental ability for any live organism. The development of …
information, which is a fundamental ability for any live organism. The development of …
Deep brain stimulation targeting the fornix for mild Alzheimer dementia: design of the ADvance randomized controlled trial
KB Holroyd, L Fosdick, GS Smith… - Open Access Journal …, 2015 - Taylor & Francis
Background: There are currently few available treatments and no cure for Alzheimer disease
(AD), a growing public health burden. Animal models and an open-label human trial have …
(AD), a growing public health burden. Animal models and an open-label human trial have …
Deep brain stimulation of fornix in Alzheimer's disease: From basic research to clinical practice
Z Liu, K Shu, Y Geng, C Cai… - European Journal of …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the most common progressive neurodegenerative
diseases associated with the degradation of memory and cognitive ability. Current …
diseases associated with the degradation of memory and cognitive ability. Current …
Deep brain stimulation targeting the fornix for mild Alzheimer dementia (the ADvance trial): a two year follow-up including results of delayed activation
JMS Leoutsakos, H Yan, WS Anderson… - Journal of …, 2018 - content.iospress.com
Background: Given recent challenges in developing new treatments for Alzheimer dementia
(AD), it is vital to explore alternate treatment targets, such as neuromodulation for circuit …
(AD), it is vital to explore alternate treatment targets, such as neuromodulation for circuit …
Symptomatic treatment of memory decline in Alzheimer's disease by deep brain stimulation: a feasibility study
D Fontaine, A Deudon, JJ Lemaire… - Journal of …, 2013 - content.iospress.com
Recent studies have suggested that memory circuits can be modulated by deep brain
stimulation (DBS). This propriety might be used to slow down cognitive decline in patients …
stimulation (DBS). This propriety might be used to slow down cognitive decline in patients …
Ethical considerations for deep brain stimulation trials in patients with early-onset Alzheimer's disease
JNM Viaña, M Bittlinger… - Journal of Alzheimer's …, 2017 - content.iospress.com
Several studies of deep brain stimulation (DBS) of the fornix or the nucleus basalis of
Meynert have been recently conducted in people with Alzheimer's disease, with several …
Meynert have been recently conducted in people with Alzheimer's disease, with several …
[HTML][HTML] Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease
AS Ríos, S Oxenford, C Neudorfer, K Butenko… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …
[HTML][HTML] A phase II study of fornix deep brain stimulation in mild Alzheimer's disease
AM Lozano, L Fosdick, MM Chakravarty… - Journal of …, 2016 - content.iospress.com
Background: Deep brain stimulation (DBS) is used to modulate the activity of dysfunctional
brain circuits. The safety and efficacy of DBS in dementia is unknown. Objective: To assess …
brain circuits. The safety and efficacy of DBS in dementia is unknown. Objective: To assess …
Current status of deep brain stimulation for Alzheimer's disease: from chance observation to clinical trials
Alzheimer's disease (AD) is a neurodegenerative disorder that results in significant memory
impairment and cognitive decline. Current medical treatment is aimed at treating AD …
impairment and cognitive decline. Current medical treatment is aimed at treating AD …
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