Antiangiogenic therapy for ischemic retinopathies

M Al-Latayfeh, PS Silva, JK Sun… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Neovascularization is a common pathological process in various retinal vascular disorders
including diabetic retinopathy (DR), age-related macular degeneration (AMD) and retinal …

Development of anti‐VEGF therapies for intraocular use: a guide for clinicians

PA Keane, SR Sadda - Journal of ophthalmology, 2012 - Wiley Online Library
Angiogenesis is the process by which new blood vessels form from existing vessel networks.
In the past three decades, significant progress has been made in our understanding of …

Treatment of retinal diseases with VEGF antagonists

RO Schlingemann, AN Witmer - Progress in brain research, 2009 - Elsevier
Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are the most
prevalent causes of blindness in the Western world. The pathogenesis of neovascularization …

Anti‐VEGF therapy and the retina: an update

V Tah, HO Orlans, J Hyer, E Casswell… - Journal of …, 2015 - Wiley Online Library
Ocular angiogenesis and macular oedema are major causes of sight loss across the world.
Aberrant neovascularisation, which may arise secondary to numerous disease processes …

Anti–vascular endothelial growth factor agents in the treatment of retinal disease: from bench to bedside

PA Campochiaro, LP Aiello, PJ Rosenfeld - Ophthalmology, 2016 - Elsevier
The association of retinal hypoxia with retinal neovascularization has been recognized for
decades, causing Michaelson to postulate in 1948 that a factor secreted by hypoxic retina …

Antineovascular agents in the treatment of eye diseases

W Eichler, Y Yafai, P Wiedemann… - Current pharmaceutical …, 2006 - ingentaconnect.com
Neovascularization is a common and potentially visually threatening complication of eye
diseases such as diabetic retinopathy (DR) and age-related macular degeneration (AMD) …

Current perspectives on established and novel therapies for pathological neovascularization in retinal disease

M Campbell, SL Doyle - Biochemical pharmacology, 2019 - Elsevier
Neovascularization is a hallmark pathology of numerous retinal diseases from diabetic
retinopathy (DR) to age-related related macular degeneration (AMD). Over the past 2 …

Pharmacologic therapy for diabetic retinopathy

R Gardlik, I Fusekova - Seminars in Ophthalmology, 2015 - Taylor & Francis
Diabetic retinopathy is one of the most serious complications of chronic diabetes mellitus
and is the leading cause of blindness in working-age populations. Large, randomized …

[HTML][HTML] Vascular endothelial growth factors and their inhibitors in ocular neovascular disorders

M Homayouni - Journal of Ophthalmic & Vision Research, 2009 - ncbi.nlm.nih.gov
The introduction of pharmacotherapy has been one of the most important advances in the
management of retinal disorders. Age-related macular degeneration (AMD) was once …

[图书][B] Anti-angiogenic therapy in ophthalmology

A Stahl - 2016 - Springer
In 2006, intraocular anti-VEGF therapy for exudative age-related macular degeneration
(AMD) was ranked among the top 10 breakthroughs of the year by Science Magazine. Since …