Prespecification and plasticity: shifting mechanisms of cell migration

P Friedl - Current opinion in cell biology, 2004 - Elsevier
Cell migration is a universal process involving different morphologies and mechanisms in
different cell types and tissue environments. Prespecified cell-type-specific patterns of cell …

Cell migration at a glance

M Vicente-Manzanares, DJ Webb… - Journal of cell …, 2005 - journals.biologists.com
The model shown represents a polarized cell that has distinct leading and trailing edges.
This is a common feature of both fibroblastic and amoeboid motility. The leading edge points …

Plasticity of cell migration: a multiscale tuning model

P Friedl, K Wolf - Journal of Cell Biology, 2010 - rupress.org
Cell migration underlies tissue formation, maintenance, and regeneration as well as
pathological conditions such as cancer invasion. Structural and molecular determinants of …

Cell migration: mechanisms of rear detachment and the formation of migration tracks

G Kirfel, A Rigort, B Borm, V Herzog - European journal of cell biology, 2004 - Elsevier
Cell migration is central to many biological and pathological processes, including
embryogenesis, tissue repair and regeneration as well as cancer and the inflammatory …

A common framework for EMT and collective cell migration

K Campbell, J Casanova - Development, 2016 - journals.biologists.com
During development, cells often switch between static and migratory behaviours. Such
transitions are fundamental events in development and are linked to harmful consequences …

[HTML][HTML] Cell migration: a physically integrated molecular process

DA Lauffenburger, AF Horwitz - cell, 1996 - cell.com
Cell migration plays a central role in a wide variety of biological phenomena. In
embryogenesis, cellular migrations are a recurring theme in important morphogenic …

[HTML][HTML] Cell migration during morphogenesis

A Aman, T Piotrowski - Developmental biology, 2010 - Elsevier
During development, functional structures must form with the correct three-dimensional
geometry composed of the correct cell types. In many cases cell types are specified at …

Collective cell migration of epithelial and mesenchymal cells

E Theveneau, R Mayor - Cellular and Molecular Life Sciences, 2013 - Springer
Directional cell migration is required for proper embryogenesis, immunity, and healing, and
its underpinning regulatory mechanisms are often hijacked during diseases such as chronic …

Plasticity of cell migration in vivo and in silico

V Te Boekhorst, L Preziosi… - Annual review of cell and …, 2016 - annualreviews.org
Cell migration results from stepwise mechanical and chemical interactions between cells
and their extracellular environment. Mechanistic principles that determine single-cell and …

[PDF][PDF] Collective cell migration in morphogenesis and cancer

P Friedl, Y Hegerfeldt, M Tusch - International Journal of Developmental …, 2004 - Citeseer
The movement of cells that maintain cell-cell junctions yet protrude along or within tissues is
an important mechanism for cell positioning in morphogenesis, tissue repair and cancer …