Autoimmune and autoinflammatory diseases are associated with severe morbidity, and
represent an impactful health and economic burden worldwide. The treatment of these …

The population of the Top End of the Northern Territory has a high incidence of several
infections of particular significance in the immunosuppressed. The following protocol for …

The incidence of some autoimmune diseases has increased dramatically in recent years in
the developed world. Many autoimmune diseases are governed by both genetic and …

Background: The widespread use of immunosuppressives in treating systemic autoimmune
disorders has resulted in opportunistic infections (OIs) following such therapy. Current data …

In recent decades, biological therapy has enabled disease activity control and improved
quality of life in patients with autoimmune diseases. These therapies that are involved in …

Despite the huge advance that antiretroviral therapy represents for the prognosis of infection
by the human immunodeficiency virus (HIV), opportunistic infections (OIs) continue to be a …

Another facet of the close link between infectious and autoimmune diseases is the infections
that arise during treatment with immunosuppressive drugs. Glucocorticoids and …

Background Pneumocystis pneumonia (PCP) is an increasing problem amongst patients on
immunosuppression with autoimmune inflammatory disorders (AID). The disease presents …

Infectious agents may induce autoimmune disease through several mechanisms, notably
antigen mimicry and inflammation of the target organ; conversely, infections may protect …

The use of immunosuppressive therapies for immune-mediated disease is associated with
an elevated risk of infections and related comorbidities. While many infectious diseases can …