Interaction of BDNF rs6265 variants and energy and protein intake in the risk for glucose intolerance and type 2 diabetes in middle-aged adults

JW Daily, S Park - Nutrition, 2017 - Elsevier
Objectives Brain-derived neurotrophic factor (BDNF) is associated with the risk for
Alzheimer's disease and type 2 diabetes. The aim of this study was to examine the …

Obesity-related parameters in carriers of some BDNF genetic variants may depend on daily dietary macronutrients intake

U Miksza, E Adamska-Patruno, W Bauer… - Scientific Reports, 2023 - nature.com
Some common single-nucleotide polymorphisms of the brain-derived neurotrophic factor
(BDNF) gene have been associated not only with the neurodegenerative diseases but also …

The BDNF Protein is Associated With Glucose Homeostasis and Food Intake in Carriers of Common BDNF Gene Variants

U Miksza, W Bauer, J Roszkowska… - The Journal of …, 2024 - academic.oup.com
Context Brain-derived neurotrophic factor (BDNF) concentrations may differ between BDNF
genotype carriers. These changes occur in individuals with metabolic and mental disorders …

Potential unfavorable impacts of BDNF Val66Met polymorphisms on metabolic risks in average population in a longevous area

JH Peng, CW Liu, SL Pan, HY Wu, QH Liang, RJ Gan… - BMC geriatrics, 2017 - Springer
Background Brain-derived neurotrophic factor (BDNF) has been implicated in cognitive
performance and the modulation of several metabolic parameters in some disease models …

The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents

A Kalenda, K Landgraf, D Löffler, P Kovacs… - Pediatric …, 2018 - Wiley Online Library
Background The amino acid‐changing exonic variant rs6265 (Val66Met polymorphism) in
the brain‐derived neurotrophic factor (BDNF) has been linked to obesity in several genotype …

Interactions of BDNF Val66met and dietary indices in relation to metabolic markers among patient with type 2 diabetes mellitus: a cross-sectional study

Z Naeini, F Abaj, M Rafiee, F Koohdani - Journal of Health, Population and …, 2023 - Springer
Background Gene–diet interaction is related to the progression of diabetes and
cardiovascular diseases biomarkers. We aimed to evaluate the interaction between diet …

Rs4074134 near BDNF gene is associated with type 2 diabetes mellitus in Chinese Han population independently of body mass index

X Han, Y Luo, X Zhang, C Lv, X Sun, X Zhang, X Zhou… - PLoS …, 2013 - journals.plos.org
Obesity and family history are the most important predictors for type 2 diabetes mellitus
(T2DM) in the Chinese Han population. However, it is not known whether the genetic loci …

Replication of the association of BDNF and MC4R variants with dietary intake in the Diabetes Prevention Program

JM McCaffery, KA Jablonski, PW Franks… - Psychosomatic …, 2017 - journals.lww.com
Objective Genomewide association studies (GWAS) have identified consistent associations
with obesity, with a number of studies implicating eating behavior as a primary mechanism …

Brain-derived neurotrophic factor Val66Met polymorphism is associated with mild cognitive impairment in elderly patients with type 2 diabetes: a case-controlled study

J Liu, W Yang, H Luo, Y Ma, H Zhao, X Dan - Aging Clinical and …, 2021 - Springer
Background Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is reported
to be associated with cognitive dysfunction, an important comorbidity factor in patients with …

Associations of the BDNF Val66Met polymorphism with body composition, cardiometabolic risk factors, and energy intake in youth with obesity: findings from the …

GS Goldfield, J Walsh, RJ Sigal, GP Kenny… - Frontiers in …, 2021 - frontiersin.org
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is functionally related
to BDNF, and is associated with obesity and metabolic complications in adults, but limited …