COVID-19 induces a hyperactive phenotype in circulating platelets

SP Comer, S Cullivan, PB Szklanna, L Weiss… - PLoS …, 2021 - journals.plos.org
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date …

Platelet functions and activities as potential hematologic parameters related to Coronavirus Disease 2019 (Covid-19)

F Salamanna, M Maglio, MP Landini, M Fini - Platelets, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a new infectious disease that currently
lacks standardized and established laboratory markers to evaluate its severity. In COVID-19 …

[HTML][HTML] Platelets contribute to disease severity in COVID‐19

TJ Barrett, S Bilaloglu, M Cornwell, HM Burgess… - Journal of Thrombosis …, 2021 - Elsevier
Objective Heightened inflammation, dysregulated immunity, and thrombotic events are
characteristic of hospitalized COVID‐19 patients. Given that platelets are key regulators of …

SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype

D Bongiovanni, M Klug, O Lazareva, S Weidlich… - Cell death & …, 2021 - nature.com
Abstract Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable
state, characterized by abnormal coagulation parameters and by increased incidence of …

Platelet activation and thrombosis in COVID-19

T Iba, H Wada, JH Levy - Seminars in Thrombosis and …, 2023 - thieme-connect.com
Although thrombosis frequently occurs in infectious diseases, the coagulopathy associated
with COVID-19 has unique characteristics. Compared with bacterial sepsis, COVID-19 …

Platelet gene expression and function in patients with COVID-19

BK Manne, F Denorme, EA Middleton… - Blood, The Journal …, 2020 - ashpublications.org
There is an urgent need to understand the pathogenesis of coronavirus disease 2019
(COVID-19). In particular, thrombotic complications in patients with COVID-19 are common …

Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients—indications for predictive, preventive, and personalized medical …

X Zhao, K Wang, P Zuo, Y Liu, M Zhang, S Xie… - Epma Journal, 2020 - Springer
Background Changes in platelet count are common in COVID-19 patients. The platelet count
reflects the thrombocyte turnover, acting as a sensitive indicator of illness severity that is of …

Platelets can associate with SARS-Cov-2 RNA and are hyperactivated in COVID-19

Y Zaid, F Puhm, I Allaeys, A Naya, M Oudghiri… - Circulation …, 2020 - Am Heart Assoc
Rationale: In addition to the overwhelming lung inflammation that prevails in coronavirus
disease 2019 (COVID-19), hypercoagulation and thrombosis contribute to the lethality of …

Platelets promote thromboinflammation in SARS-CoV-2 pneumonia

F Taus, G Salvagno, S Canè, C Fava… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome
coronavirus 2 pneumonia. Aim was to investigate whether subpopulations of platelets were …

[HTML][HTML] Platelets and COVID-19

AK Rohlfing, D Rath, T Geisler, M Gawaz - Hämostaseologie, 2021 - thieme-connect.com
In 2019 first reports about a new human coronavirus emerged, which causes common cold
symptoms as well as acute respiratory distress syndrome. The virus was identified as severe …