[HTML][HTML] Exosomes as a tumor immune escape mechanism: possible therapeutic implications

TE Ichim, Z Zhong, S Kaushal, X Zheng, X Ren… - Journal of translational …, 2008 - Springer
Advances in cancer therapy have been substantial in terms of molecular understanding of
disease mechanisms, however these advances have not translated into increased survival …

New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies

AS Pathania, P Prathipati, KB Challagundla - Biochimica Et Biophysica Acta …, 2021 - Elsevier
Recent advances in extracellular vesicle biology have uncovered a substantial role in
maintaining cell homeostasis in health and disease conditions by mediating intercellular …

Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

AJ Abusamra, Z Zhong, X Zheng, M Li, TE Ichim… - Blood Cells, Molecules …, 2005 - Elsevier
Tumor-derived immune suppression is considered to be a major mechanism of tumor
evasion from the immune system destruction, however, little is known regarding the …

Exosomes and cancer: a newly described pathway of immune suppression

HG Zhang, WE Grizzle - Clinical Cancer Research, 2011 - AACR
Exosomes are small (30 to 100 nm) membrane-bound particles that are released from
normal, diseased, and neoplastic cells and are present in blood and other bodily fluids …

[HTML][HTML] Regulation of antitumor immune responses by exosomes derived from tumor and immune cells

A Rincón-Riveros, L Lopez, EV Villegas… - Cancers, 2021 - mdpi.com
Simple Summary A lot of interest has been placed into extracellular vesicles as an
intercellular communication mechanism with potential clinical application. As these vesicles …

[HTML][HTML] More insights into the immunosuppressive potential of tumor exosomes

V Huber, P Filipazzi, M Iero, S Fais… - Journal of Translational …, 2008 - Springer
We did read with great interest the recent review published by Ichim et al on the potential
role of tumor exosomes as immune escape mechanism [1], and we were pleased to see that …

Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation

P Altevogt, NP Bretz, J Ridinger, J Utikal… - Seminars in cancer …, 2014 - Elsevier
The immune system of cancer patients is often suppressed. Accumulating evidence
suggests that exosomes released from tumor cells may play an essential role in this process …

[HTML][HTML] Exosome-mediated immunosuppression in tumor microenvironments

QH Xie, JQ Zheng, JY Ding, YF Wu, L Liu, ZL Yu… - Cells, 2022 - mdpi.com
Exosomes are membranous structures secreted by nearly all cell types. As critical
messengers for intercellular communication, exosomes deliver bioactive cargoes to …

The immunomodulation potential of exosomes in tumor microenvironment

M Wang, B Zhang - Journal of Immunology Research, 2021 - Wiley Online Library
Exosomes are lipid bilayer particles that originated from almost all types of cells and play an
important role in intercellular communication. Tumor‐derived exosomes contain large …

[HTML][HTML] Roles of exosomes in immunotherapy for solid cancers

C Lyu, H Sun, Z Sun, Y Liu, Q Wang - Cell Death & Disease, 2024 - nature.com
Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …