Nanodrugs represent novel solutions to reshuffle repurposed drugs for cancer therapy. They
might offer different therapeutic options by combining targeted drug delivery and imaging in …

Over the past decades, research has made impressive breakthroughs towards drug delivery
systems, resulting in a wide range of multifunctional engineered nanoparticles with …

Multiple studies about tumor biology have revealed the determinant role of the tumor
microenvironment in cancer progression, resulting from the dynamic interactions between …

Nanomedicines have been investigated for delivering drugs to tumors due to their ability to
accumulate in the tumor tissues. 2D in vitro cell culture has been used to investigate the …

Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …

The complexity and diversity of the biochemical processes that occur during tumorigenesis
and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two …

For decades, 2D cell culture format on plastic has been the main workhorse in cancer
research. Though many important understandings of cancer cell biology were derived using …

Recent years have witnessed dramatic improvements in nanotechnology-based cancer
therapeutics, and it continues to evolve from the use of conventional therapies …

Stimuli-responsive drug-delivery systems (DDSs) have emerged as a potential tool for
applications in healthcare, mainly in the treatment of cancer where versatile nanocarriers …

Advances in nanotechnology are providing to medicine a new dimension. Multifunctional
nanomaterials with diagnostics and treatment modalities integrated in one nanoparticle or in …