Currently, 60 million women of reproductive age (18-44 years old) worldwide, and
approximately 3 million American women have diabetes mellitus, and it has been estimated …

Diabetes is an increasingly common diagnosis among pregnant women. Pregestational
diabetes is associated with an increase in many adverse pregnancy outcomes, which impact …

Maternal diabetes-induced birth defects occur in 6-10% of babies born to mothers with
pregestational diabetes, representing a significant maternal-fetal health problem. Currently …

BACKGROUND Maternal pregestational diabetes is a well‐known risk factor for congenital
anomalies. This study analyses the spectrum of congenital anomalies associated with …

OBJECTIVE Women with diabetes in pregnancy have high rates of pregnancy
complications. Our aims were to explore trends in the incidence of diabetes in pregnancy …

Introduction Pregestational and gestational diabetes mellitus (PGDM; GDM) are significant
health concerns because they are associated with an increased rate of malformations and …

OBJECTIVE: The purpose of this study was to examine associations between diabetes
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …

Birth defects are the leading cause of infant mortality in the United States, which has one of
the highest infant mortality rates in the developed world. Many of these birth defects can be …

Background The risk of major congenital malformations (MCM) is increased in women with
pregestational diabetes mellitus (PGDM). Whether this risk is increased in gestational …

Embryos exposed to high glucose exhibit aberrant maturational and cytoarchitectural
cellular changes, implicating cellular organelle stress in diabetic embryopathy. c-Jun-N …