[HTML][HTML] Birth defects in pregestational diabetes: Defect range, glycemic threshold and pathogenesis
R Gabbay-Benziv, EA Reece, F Wang… - World journal of …, 2015 - ncbi.nlm.nih.gov
Currently, 60 million women of reproductive age (18-44 years old) worldwide, and
approximately 3 million American women have diabetes mellitus, and it has been estimated …
approximately 3 million American women have diabetes mellitus, and it has been estimated …
Pregestational diabetes in pregnancy: Complications, management, surveillance, and mechanisms of disease—A review
A Shub, M Lappas - Prenatal diagnosis, 2020 - Wiley Online Library
Diabetes is an increasingly common diagnosis among pregnant women. Pregestational
diabetes is associated with an increase in many adverse pregnancy outcomes, which impact …
diabetes is associated with an increase in many adverse pregnancy outcomes, which impact …
Decoding the oxidative stress hypothesis in diabetic embryopathy through proapoptotic kinase signaling
Maternal diabetes-induced birth defects occur in 6-10% of babies born to mothers with
pregestational diabetes, representing a significant maternal-fetal health problem. Currently …
pregestational diabetes, representing a significant maternal-fetal health problem. Currently …
Spectrum of congenital anomalies in pregnancies with pregestational diabetes
E Garne, M Loane, H Dolk, I Barisic… - … Research Part A …, 2012 - Wiley Online Library
BACKGROUND Maternal pregestational diabetes is a well‐known risk factor for congenital
anomalies. This study analyses the spectrum of congenital anomalies associated with …
anomalies. This study analyses the spectrum of congenital anomalies associated with …
Trends in incidence of diabetes in pregnancy and serious perinatal outcomes: a large, population-based study in Ontario, Canada, 1996–2010
OBJECTIVE Women with diabetes in pregnancy have high rates of pregnancy
complications. Our aims were to explore trends in the incidence of diabetes in pregnancy …
complications. Our aims were to explore trends in the incidence of diabetes in pregnancy …
Effect of maternal diabetes on the embryo, fetus, and children: congenital anomalies, genetic and epigenetic changes and developmental outcomes
A Ornoy, EA Reece, G Pavlinkova… - … Research Part C …, 2015 - Wiley Online Library
Introduction Pregestational and gestational diabetes mellitus (PGDM; GDM) are significant
health concerns because they are associated with an increased rate of malformations and …
health concerns because they are associated with an increased rate of malformations and …
Diabetes mellitus and birth defects
OBJECTIVE: The purpose of this study was to examine associations between diabetes
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …
Diabetes-induced birth defects: what do we know? What can we do?
EA Reece - Current diabetes reports, 2012 - Springer
Birth defects are the leading cause of infant mortality in the United States, which has one of
the highest infant mortality rates in the developed world. Many of these birth defects can be …
the highest infant mortality rates in the developed world. Many of these birth defects can be …
Major congenital malformations in women with gestational diabetes mellitus: a systematic review and meta‐analysis
M Balsells, A García‐Patterson, I Gich… - … research and reviews, 2012 - Wiley Online Library
Background The risk of major congenital malformations (MCM) is increased in women with
pregestational diabetes mellitus (PGDM). Whether this risk is increased in gestational …
pregestational diabetes mellitus (PGDM). Whether this risk is increased in gestational …
c-Jun NH2-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy
X Li, C Xu, P Yang - Diabetes, 2013 - Am Diabetes Assoc
Embryos exposed to high glucose exhibit aberrant maturational and cytoarchitectural
cellular changes, implicating cellular organelle stress in diabetic embryopathy. c-Jun-N …
cellular changes, implicating cellular organelle stress in diabetic embryopathy. c-Jun-N …