[HTML][HTML] Cardiac-Adaptive Conductive Hydrogel Patch Enabling Construction of Mechanical–Electrical Anisotropic Microenvironment for Heart Repair

X Song, J Zhang, S Shen, D Liu, J Zhang, W Yin, G Ye… - Research, 2023 - spj.science.org
The biomimetic construction of a microstructural–mechanical–electrical anisotropic
microenvironment adaptive to the native cardiac tissue is essential to repair myocardial …

[HTML][HTML] Electrically conductive hydrogel-based micro-topographies for the development of organized cardiac tissues

A Navaei, N Moore, RT Sullivan, D Truong… - RSC …, 2017 - pubs.rsc.org
The dense uniaxially aligned cardiac cytoarchitecture of the myocardium along with
electrical and mechanical coupling between the cardiac cells are key factors in the …

Conductive hydrogel patches with high elasticity and fatigue resistance for cardiac microenvironment remodeling

T Shi, P Wang, Y Ren, W Zhang, J Ma, S Li… - … applied materials & …, 2023 - ACS Publications
Remodeling the conductive zone to assist normal myocardial contraction and relaxation
during myocardial fibrosis has become the primary concern of myocardial infarction (MI) …

A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair

X Song, X Wang, J Zhang, S Shen, W Yin, G Ye… - Biomaterials, 2021 - Elsevier
Conductive hydrogel is a potential therapeutic tool to treat damaged heart muscles in
myocardial infarction (MI). However, it is still a quite challenge to optimize the fabrication of a …

An anisotropic electromagnetic hydrogel promotes cardiomyocyte maturation and post-infarction cardiac repair

X Li, P Lu, Z Liu, Z Wen, X Li, C Wang, W Jin… - Chemical Engineering …, 2023 - Elsevier
Effective therapies for myocardial infarction (MI) are essential in lowering associated
mortality rates. While hydrogel-based patch therapy has shown promise in improving post …

Effects of electrically conductive nano-biomaterials on regulating cardiomyocyte behavior for cardiac repair and regeneration

M Morsink, P Severino, E Luna-Ceron, MA Hussain… - Acta biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) represents one of the most prevalent cardiovascular diseases,
with a highly relevant and impactful role in public health. Despite the therapeutic advances …

Engineering a naturally-derived adhesive and conductive cardiopatch

BW Walker, RP Lara, CH Yu, ES Sani, W Kimball… - Biomaterials, 2019 - Elsevier
Myocardial infarction (MI) leads to a multi-phase reparative process at the site of damaged
heart that ultimately results in the formation of non-conductive fibrous scar tissue. Despite …

A polyphenol-derived redox-active and conductive nanoparticle-reinforced hydrogel with wet adhesiveness for myocardial infarction repair by simultaneously …

P Chen, W Zhang, X Fan, X Shi, Y Jiang, L Yan, H Li… - Nano Today, 2024 - Elsevier
Myocardial infarction (MI) is one major cause of death worldwide. Safe and effective fixation
of a functional cardiac patch onto the wet and dynamic myocardium is desired for clinical …

An intrapericardial injectable hydrogel patch for mechanical–electrical coupling with infarcted myocardium

C Yu, Z Yue, M Shi, L Jiang, S Chen, M Yao, Q Yu… - ACS …, 2022 - ACS Publications
Although hydrogel-based patches have shown promising therapeutic efficacy in myocardial
infarction (MI), synergistic mechanical, electrical, and biological cues are required to restore …

Engineered extracellular microenvironment with a tunable mechanical property for controlling cell behavior and cardiomyogenic fate of cardiac stem cells

MY Choi, JT Kim, WJ Lee, Y Lee, KM Park, YI Yang… - Acta biomaterialia, 2017 - Elsevier
Endogenous cardiac stem cells (CSCs) are known to play a certain role in the myocardial
homeostasis of the adult heart. The extracellular matrix (ECM) surrounding CSCs provides …