Dopamine and reward seeking: the role of ventral tegmental area

R Ranaldi - Reviews in the Neurosciences, 2014 - degruyter.com
Reward seeking is controlled by conditioned stimuli (CSs). There is a positive relation
between mesocorticolimbic dopamine (DA) and the performance of learned reward-directed …

How conditioned stimuli acquire the ability to activate VTA dopamine cells: a proposed neurobiological component of reward-related learning

MR Zellner, R Ranaldi - Neuroscience & Biobehavioral Reviews, 2010 - Elsevier
The ability to learn about conditioned stimuli (CS) associated with rewards is a crucial
adaptive mechanism. Activity in the mesocorticolimbic dopamine (DA) system, as well as in …

Dopamine signaling in the dorsomedial striatum promotes compulsive behavior

JL Seiler, CV Cosme, VN Sherathiya, MD Schaid… - Current Biology, 2022 - cell.com
Compulsive behavior is a defining feature of disorders such as substance use disorders.
Current evidence suggests that corticostriatal circuits control the expression of established …

Reward‐guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico‐basal ganglia networks

HH Yin, SB Ostlund, BW Balleine - European Journal of …, 2008 - Wiley Online Library
Here we challenge the view that reward‐guided learning is solely controlled by the
mesoaccumbens pathway arising from dopaminergic neurons in the ventral tegmental area …

A concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotine

R Eddine, S Valverde, S Tolu, D Dautan, A Hay… - Scientific reports, 2015 - nature.com
Midbrain dopamine (DA) neurons are key players in motivation and reward processing.
Increased DA release is thought to be central in the initiation of drug addiction. Whereas …

Chapter VI Dopamine, motivation and reward

G Di Chiara - Handbook of chemical neuroanatomy, 2005 - Elsevier
Experimental manipulation of dopamine (DA) transmission by lesions and drugs indicates a
role in the acquisition and expression of behavior motivated by conventional and drug …

Neurobiology of reward-related learning

E Galaj, R Ranaldi - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
A major goal in psychology is to understand how environmental stimuli associated with
primary rewards come to function as conditioned stimuli, acquiring the capacity to elicit …

Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory

S Ikemoto - Neuroscience & biobehavioral reviews, 2010 - Elsevier
Reductionist attempts to dissect complex mechanisms into simpler elements are necessary,
but not sufficient for understanding how biological properties like reward emerge out of …

The dopamine hypothesis of reward: past and current status

R Spanagel, F Weiss - Trends in neurosciences, 1999 - cell.com
Mesolimbic dopaminergic neurons are thought to serve as a final common neural pathway
for mediating reinforcement processes. However, several recent findings have challenged …

The effects of systemic and intracerebral injections of D1 and D2 agonists on brain stimulation reward

R Ranaldi, RJ Beninger - Brain research, 1994 - Elsevier
That dopamine (DA) plays a role in reward-related learning is well documented but the
mechanisms through which it acts are not well understood. The present set of experiments …