Cholesterol accumulation in macrophages leads to the formation of foam cells and
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …

The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Background The production of lipid-laden cells in macrophages after significant ingestion of
oxidized low-density lipoprotein is considered the most critical phase in the creation of …

Resveratrol has been shown to exert anti-atherosclerotic effects. 5'AMP-activated protein
kinase (AMPK) and monocyte chemotactic protein-1 (MCP-1) play key roles in foam cell …

Purpose. Hydroxytyrosol (HT) processes multiaspect pharmacological properties such as
antithrombosis and antidiabetes. The aim of this study was to explore the antistherosclerotic …

Cholesterol efflux from macrophages is the first step of reverse cholesterol transport (RCT),
whose increase inhibits cholesterol accumulation and foam cell formation to suppress …

The accumulation of foam cells in atherosclerotic lesions is a hallmark of early-stage
atherosclerosis. Kaempferol has been shown to inhibit oxidized low-density lipoprotein …

Numerous studies have shown that the formation of foam cells is of vital importance in the
process of atherosclerosis. The aim of the present study was to assess the effects of …

Cholesterol-laden macrophages trigger accumulation of foam cells and increase the risk of
developing atherosclerosis. We hypothesized that quercetin could lower the content of …

Formation of macrophage‐derived foam cells is a hallmark in earlier stages of
atherosclerosis (AS). Increased cholesterol efflux from macrophage foam cells promote …