Resveratrol prevents cognitive deficits by attenuating oxidative damage and inflammation in rat model of streptozotocin diabetes induced vascular dementia

SS Gocmez, TD Şahin, Y Yazir, G Duruksu… - Physiology & …, 2019 - Elsevier
Diabetes is one of the risk factors for the development of vascular dementia (VD), leading to
endothelial dysfunction and cognitive impairment. Resveratrol has been shown to have …

Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia

X Ma, Z Sun, Y Liu, Y Jia, B Zhang… - Neural regeneration …, 2013 - journals.lww.com
Resveratrol possesses beneficial biological effects, which include anti-oxidant, anti-
inflammatory and anti-carcinogenic properties. Recently, resveratrol has been shown to …

Effects of resveratrol on learning and memory in rats with vascular dementia

Y Zhang, Y Li, Y Wang, G Wang… - Molecular …, 2019 - spandidos-publications.com
The purpose of the present study was to study the effects of resveratrol on cognitive function
in rats with vascular dementia and to investigate the molecular mechanisms of its …

Resveratrol reverses the synaptic plasticity deficits in a chronic cerebral hypoperfusion rat model

H Li, J Wang, P Wang, Y Rao, L Chen - Journal of Stroke and …, 2016 - Elsevier
Background Dementia is the most prevalent neurological disease in aged people. Chronic
cerebral hypoperfusion (CCH) is one of the causes of vascular dementia (VaD) and is also …

Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats

DM Arrick, H Sun, KP Patel… - American Journal of …, 2011 - journals.physiology.org
Decreased dilation of cerebral arterioles via an increase in oxidative stress may be a
contributing factor in the pathogenesis of diabetes-induced complications leading to …

Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic …

X Tian, Y Liu, G Ren, L Yin, X Liang, T Geng, H Dang… - Brain research, 2016 - Elsevier
Many patients with diabetes are at increased risk of cognitive dysfunction and dementia.
Resveratrol, a polyphenol found mainly in grapes and red wine, has antioxidant, anti …

Cerebroprotective effect of resveratrol through antioxidant and anti-inflammatory effects in diabetic rats

O Prabhakar - Naunyn-Schmiedeberg's archives of pharmacology, 2013 - Springer
Oxidative stress and inflammation have been implicated in cerebral ischemia/reperfusion
injury and complication of diabetes. The present study was designed to evaluate whether …

Neurodegeneration in streptozotocin-induced diabetic rats is attenuated by treatment with resveratrol

YH Jing, KH Chen, PC Kuo, CC Pao, JK Chen - Neuroendocrinology, 2013 - karger.com
Aim: Diabetes mellitus-associated hyperglycemia and oxidative stress have been shown to
have detrimental effects on the brain and may lead to impairment of cognitive functions …

Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH …

P Toth, S Tarantini, Z Tucsek… - American Journal …, 2014 - journals.physiology.org
Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via
neurovascular coupling is essential for the maintenance of normal neuronal function …

Long-term administration of resveratrol at low doses improves neurocognitive performance as well as cerebral blood flow and modulates the inflammatory pathways in …

P Garrigue, L Mounien, S Champion, Y Mouhajir… - The Journal of …, 2021 - Elsevier
There is an increasing prevalence of coincident cerebrovascular deficiency and cognitive
dysfunction with aging. Increased oxidative stress as well as inflammation that occurs with …