Background The study aimed to evaluate the relationship of IL-1B/IL-1RN polymorphisms to
the predisposition of head and neck cancer (HNC) in a Chinese Han population. Methods …

Aim The incidence of head and neck cancer (HNC) is increasing but its pathogenic factors
are complex. Changes in both internal (genetic) and external (environmental) causes HNC …

AIMS: Interleukin-1β (IL-1β) is a multifunctional cytokine that up-regulates the inflammatory
response and participates in carcinogenesis, malignant transformation, tumour growth …

Purpose Previous studies have reported the association of an insertion/deletion (Ins/Del)
polymorphism (rs3783553) in the 3′ untranslated region of interleukin-1A (IL-1A) with the …

Previous studies demonstrated that the polymorphism of interleukin‐1 (IL‐1) produce
alterations of the protein expression and may contribute to oncogenetic processes. The aim …

Nasopharyngeal carcinoma (NPC) is one of the most common cancers in southern China. In
addition to environmental factors such as Epstein-Barr virus infection and chemical …

Abstract Background Interleukin‐1β (IL‐1B) has been recognized as a pro‐inflammatory
cytokine and associated with tumorigenesis. We aimed to evaluate the contribution of IL‐1B …

Background Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, is emerging as a key
mediator of carcinogenesis that characterizes host-environment interactions …

Background The association of interleukin-10 rs1800896 polymorphism with head and neck
cancer risk and its clinical stages has been investigated by many published studies, but the …

Cancer incidence is dramatically increasing worldwide, therefore improved prediction and
therapeutic methods are needed. Single nucleotide polymorphisms in cytokine genes may …