Interference reduction biosensing strategy for highly sensitive microRNA detection

F Chen, G Li, C Wu, L Wang, CN Ko, DL Ma… - Analytical …, 2022 - ACS Publications
MicroRNAs are potential biomarkers for human cancers and other diseases due to their
roles as post-transcriptional regulators for gene expression. However, the detection of …

Sensitive and specific microRNA detection by RNA dependent DNA ligation and rolling circle optical signal amplification

C Zhou, R Huang, X Zhou, D Xing - Talanta, 2020 - Elsevier
MicroRNAs (miRNAs) have been regarded as potential biomarkers in early diagnosis of
cancer. Since the high sequence similarity among miRNA family members, biosensing …

A target-triggered dual amplification strategy for sensitive detection of microRNA

W Lv, J Zhao, B Situ, B Li, W Ma, J Liu, Z Wu… - Biosensors and …, 2016 - Elsevier
The accurate and quantitative analysis of microRNA (miRNA) expression is critical for
biomedical research and clinical theranostics. In this study, we report a novel sensor for the …

Nicking-enhanced rolling circle amplification for sensitive fluorescent detection of cancer-related microRNAs

Z Gao, C Wu, S Lv, C Wang, N Zhang, S Xiao… - Analytical and …, 2018 - Springer
In this study, a biosensing system based on nicking-enhanced rolling circle amplification (N-
RCA) was proposed for the highly sensitive detection of cancer-related let-7a microRNA …

Target-triggered enzyme-free amplification strategy for sensitive detection of microRNA in tumor cells and tissues

Y Liao, R Huang, Z Ma, Y Wu, X Zhou… - Analytical chemistry, 2014 - ACS Publications
MicroRNAs (miRNAs) participate in important processes of life course. Because of their
characters of small sizes, vulnerable degradabilities, and sequences similarities, the existing …

Linear-hairpin variable primer RT-qPCR for MicroRNA

L Lan, Q Guo, H Nie, C Zhou, Q Cai, J Huang… - Chemical …, 2019 - pubs.rsc.org
Here, we present a highly specific, sensitive and cost-effective system to quantify microRNA
(miRNA) expression based on two-step RT-qPCR with EvaGreen detection chemistry, called …

Highly sensitive and selective microRNA detection based on DNA-bio-bar-code and enzyme-assisted strand cycle exponential signal amplification

H Dong, X Meng, W Dai, Y Cao, H Lu, S Zhou… - Analytical …, 2015 - ACS Publications
Herein, a highly sensitive and selective microRNA (miRNA) detection strategy using DNA-
bio-bar-code amplification (BCA) and Nb· BbvCI nicking enzyme-assisted strand cycle for …

Emerging isothermal amplification technologies for microRNA biosensing: Applications to liquid biopsies

G Gines, R Menezes, W Xiao, Y Rondelez… - Molecular Aspects of …, 2020 - Elsevier
The potential of microRNAs (miRNAs) as biomarker candidates in clinical practice for
diagnosis, prognosis and treatment response prediction, especially in liquid biopsies, has …

Ultrasensitive quantitation of MicroRNAs via magnetic beads-based chemiluminesent assay

B Zhou, H Yang, Y Deng, M Liu, B Liu, N He… - Science China …, 2016 - Springer
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-
transcriptional level, and their aberrant expression occurs during the development of …

Two-tailed RT-qPCR: a novel method for highly accurate miRNA quantification

P Androvic, L Valihrach, J Elling, R Sjoback… - Nucleic acids …, 2017 - academic.oup.com
MicroRNAs are a class of small non-coding RNAs that serve as important regulators of gene
expression at the posttranscriptional level. They are stable in body fluids and pose great …