Polymorphic Sites at the 3' Untranslated Region of the HLA-G Gene Are Associated with Differential hla-g Soluble Levels in the Brazilian and French Population

G Martelli-Palomino, JA Pancotto, YC Muniz… - PloS one, 2013 - journals.plos.org
HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows
lower frequency of polymorphism at the coding region but higher variability at regulatory …

The genetic structure of 3′ untranslated region of the HLA-G gene: polymorphisms and haplotypes

EC Castelli, CT Mendes-Junior, NHS Deghaide… - Genes & …, 2010 - nature.com
The HLA-G gene is predominantly expressed at the maternal–fetal interface. It has been
associated with maternal–fetal tolerance and in the inhibition of cytotoxic T lymphocyte and …

A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution

EC Castelli, CT Mendes-Junior… - Molecular biology …, 2011 - academic.oup.com
HLA-G molecule plays an important role on immune response regulation and has been
implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of …

Haplotypes of the HLA-G 3' Untranslated Region Respond to Endogenous Factors of HLA-G+ and HLA-G- Cell Lines Differentially

I Poras, L Yaghi, G Martelli-Palomino… - PloS one, 2017 - journals.plos.org
The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in
cancer invasion and acceptance of allografts. The 5'and 3'regulatory regions of the HLA-G …

HLA-G UTR haplotype conservation in the Malian population: association with soluble HLA-G

F Carlini, K Traore, N Cherouat, P Roubertoux… - PloS one, 2013 - journals.plos.org
The HLA-G molecule plays an important role in immunomodulation. In a previous study
carried out on a southern French population our team showed that HLA-G haplotypes …

HLA‐G alleles and HLA‐G 14 bp polymorphisms in a Brazilian population

EC Castelli, CT Mendes‐Junior, EA Donadi - Tissue antigens, 2007 - Wiley Online Library
Brazilians represent one of the most heterogeneous populations in the world as the result of
five centuries of interethnic crosses. We investigated the polymorphism of the HLA‐G locus …

HLA-G 3′ untranslated region polymorphisms are associated with systemic lupus erythematosus in 2 Brazilian populations

N Lucena-Silva, VSB de Souza, RG Gomes… - The Journal of …, 2013 - jrheum.org
Objective. HLA-G has well recognized tolerogenic properties in physiological and
nonphysiological conditions. The 3′ untranslated region (3′ UTR) of the HLA-G gene has …

Genetic association between HLA-G 14-bp polymorphism and diseases: A systematic review and meta-analysis

BS de Almeida, YCN Muniz, AH Prompt, EC Castelli… - Human immunology, 2018 - Elsevier
Background HLA-G is an immune checkpoint molecule. Since a differential molecule
expression has been reported even for healthy individuals, many studies have focused on …

HLA‐G: Function, polymorphisms and pathology

A Arnaiz‐Villena, I Juarez… - International Journal …, 2021 - Wiley Online Library
HLA‐G immune modulatory genes and molecules are presently being studied by a
widespread number of research groups. In the present study, we do not aim to be exhaustive …

The role of the HLA-G gene and molecule on the clinical expression of rheumatologic diseases

CV Brenol, TD Veit, JAB Chies… - Revista Brasileira de …, 2012 - SciELO Brasil
Human leukocyte antigen G (HLA-G) is a non-classic class I major histocompatibility
complex (MHC) molecule characterized by low polymorphism in its coding region, a limited …