The prospects for developing a vaccine against Stapphylococcus aureus

JC Lee - Trends in microbiology, 1996 - Elsevier
Staphyloccus aureus is an important bacterial pathogen with multiple virulence factors. The
prevalence of antibiotic resistance among clinical isolates means that new vaccine …

Staphylococcal vaccines and immunotherapies

AC Schaffer, JC Lee - Infectious disease clinics of North America, 2009 - Elsevier
Staphylococcus aureus is an important pathogen in the hospital and in the community, and it
is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S …

Progress Toward a Staphylococcus aureus Vaccine

RS Daum, B Spellberg - Clinical Infectious Diseases, 2012 - academic.oup.com
High attack rates and the ability of Staphylococcus aureus to develop resistance to all
antibiotics in medical practice heightens the urgency for vaccine development. S. aureus …

Staphylococcus aureus: the current state of disease, pathophysiology and strategies for prevention

GH Dayan, N Mohamed, IL Scully, D Cooper… - Expert review of …, 2016 - Taylor & Francis
Staphylococcus aureus is both a commensal organism and also an important opportunistic
human pathogen, causing a variety of community and hospital-associated pathologies, such …

Staphylococcal vaccines

CA Michie - TRENDS in Immunology, 2002 - cell.com
Vaccination has proved relatively unsuccessful against the common mammalian commensal
bacteria Staphylococcus, despite almost a century of experimentation. Recent progress in …

Strategies for and advances in the development of Staphylococcus aureus prophylactic vaccines

J Broughan, R Anderson, AS Anderson - Expert review of vaccines, 2011 - Taylor & Francis
Staphylococcus aureus is a common human commensal organism and also a major cause
of nosocomial infections worldwide associated with high death rates, prolonged …

Development of a vaccine against Staphylococcus aureus

B Spellberg, R Daum - Seminars in immunopathology, 2012 - Springer
A vaccine to prevent infections caused by Staphylococcus aureus would have a
tremendously beneficial impact on public health. In contrast to typical encapsulated bacterial …

[PDF][PDF] Recent developments for Staphylococcus aureus vaccines: clinical and basic science challenges

RA Proctor - Eur Cell Mater, 2015 - ecmjournal.org
Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

J Clegg, E Soldaini, RM McLoughlin… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …

Immunotherapeutic strategies to combat staphylococcal infections

K Ohlsen, U Lorenz - International Journal of Medical Microbiology, 2010 - Elsevier
Antibiotic-resistant staphylococci are the leading cause of nosocomial infections in many
hospitals around the world. Meanwhile, methicillin-resistant Staphylococcus aureus (MRSA) …