Natural killer (NK) cells are the key immune effectors with the ability to mediate selection and
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …

Highlights•NK cells are effectors of selection and differentiation of CSCs/undifferentiated
tumors.•Induction of split anergy in NK cells is a mechanism for differentiation of tumor …

We have previously demonstrated that natural killer (NK) cells are the main immune
effectors that can mediate selection and differentiation of different cancer stem cells and …

It is well established that natural killer (NK) cells play an important role in the immunity
against cancer, while the involvement of other recently identified, NK-related innate …

The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …

Historically, the name of natural killer (NK) cells came from their natural ability to kill tumor
cells in vitro. From the 1970s to date, accumulating data highlighted the importance of NK …

Natural Killer (NK) cells are innate immune effectors that are primarily involved in
immunosurveillance to spontaneously eliminate malignantly transformed and virally infected …

The detection and killing of neoplastic cells require coordination of a variety of antitumor
effector cells. Natural killer (NK) cells of the innate immune system are at the forefront of the …

Natural killer (NK) cells belong to the innate immune system and were initially described
functionallywise by their spontaneous cytotoxic potential against transformed or virus …

Natural killer (NK) cells are central components of the innate immunity. In murine models, it
has been shown that NK cells can control both local tumor growth and metastasis due to …