The immunology of Epstein-Barr virus–induced disease

GS Taylor, HM Long, JM Brooks… - Annual review of …, 2015 - annualreviews.org
Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …

The Epstein-Barr virus and the immune system

G Tosato - Advances in cancer research, 1987 - Elsevier
Publisher Summary This chapter focuses on both on the effects of Epstein–Barr virus (EBV)
on human B cells and on the immune response to viral infection. The chapter also presents …

Immune escape by Epstein–Barr virus associated malignancies

C Münz, A Moormann - Seminars in cancer biology, 2008 - Elsevier
Persistent Epstein–Barr virus (EBV) infection remains asymptomatic in the majority of virus
carriers, despite the potent growth transforming potential of this virus. The increased …

Biological aspects of Epstein–Barr virus (EBV)-infected lymphocytes in chronic active EBV infection and associated malignancies

H Kanegane, K Nomura, T Miyawaki… - Critical reviews in oncology …, 2002 - Elsevier
Most primary Epstein–Barr virus (EBV) infections are clinically inapparent, but occasionally
EBV infection can cause acute infectious mononucleosis. EBV has been linked to a variety …

The biology of Epstein-Barr virus: lessons learned from the virus and the host

JI Cohen - Current opinion in immunology, 1999 - Elsevier
Recent studies indicate that a large proportion of cytotoxic T cells are directed towards the
Epstein-Barr virus (EBV) during both acute infection and convalescence. The virus, in turn …

The interplay between Epstein–Barr virus and B lymphocytes: implications for infection, immunity, and disease

OL Hatton, A Harris-Arnold, S Schaffert, SM Krams… - Immunologic …, 2014 - Springer
Human B cells are the primary targets of Epstein–Barr virus (EBV) infection. In most cases,
EBV infection is asymptomatic because of a highly effective host immune response, but …

Epstein-Barr virus: Biology and clinical disease

B Damania, SC Kenney, N Raab-Traub - Cell, 2022 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

Epstein-Barr virus-associated lymphoproliferative disorders in immunocompromised individuals

JA Thomas, MJ Allday, DH Crawford - Advances in cancer research, 1991 - Elsevier
Publisher Summary The Epstein–Barr virus (EBV) acts as one of a number of factors
including environmental and genetic elements that contribute to the pathogenesis of Burkitt's …

Asymptomatic primary infection with Epstein-Barr virus: observations on young adult cases

RJ Abbott, A Pachnio, I Pedroza-Pacheco… - Journal of …, 2017 - Am Soc Microbiol
Epstein-Barr virus (EBV) is typically acquired asymptomatically in childhood. In contrast,
infection later in life often leads to infectious mononucleosis (IM), a febrile illness …

Immunological aspects of Epstein–Barr virus infection

S Ohga, A Nomura, H Takada, T Hara - Critical reviews in oncology …, 2002 - Elsevier
Epstein–Barr virus (EBV) is a member of ubiquitous γ herpes viruses, which primarily
induces acute infectious mononucleosis (IM) or subclinical infection in susceptible subjects …