[HTML][HTML] Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection
CB Sturdevant, SB Joseph, G Schnell, RW Price… - PLoS …, 2015 - journals.plos.org
Compartmentalized HIV-1 replication within the central nervous system (CNS) likely
provides a foundation for neurocognitive impairment and a potentially important tissue …
provides a foundation for neurocognitive impairment and a potentially important tissue …
Human immunodeficiency virus type 1 RNA detected in the central nervous system (CNS) after years of suppressive antiretroviral therapy can originate from a …
SB Joseph, LP Kincer, NM Bowman… - Clinical Infectious …, 2019 - academic.oup.com
Background Human immunodeficiency virus type 1 (HIV-1) populations are detected in
cerebrospinal fluid (CSF) of some people on suppressive antiretroviral therapy (ART) …
cerebrospinal fluid (CSF) of some people on suppressive antiretroviral therapy (ART) …
Compartmentalized human immunodeficiency virus type 1 present in cerebrospinal fluid is produced by short-lived cells
PR Harrington, DW Haas, K Ritola… - Journal of virology, 2005 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS)
during primary infection and persists in this compartment by unknown mechanisms over the …
during primary infection and persists in this compartment by unknown mechanisms over the …
[HTML][HTML] HIV-1 replication in the central nervous system occurs in two distinct cell types
G Schnell, S Joseph, S Spudich, RW Price… - PLoS …, 2011 - journals.plos.org
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system (CNS)
can lead to the development of HIV-1-associated dementia (HAD). We examined the …
can lead to the development of HIV-1-associated dementia (HAD). We examined the …
[HTML][HTML] Early antiretroviral therapy is associated with lower HIV DNA molecular diversity and lower inflammation in cerebrospinal fluid but does not prevent the …
Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist
in the central nervous system (CNS), possibly contributing to inflammation, brain damage …
in the central nervous system (CNS), possibly contributing to inflammation, brain damage …
Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy
To design effective eradication strategies, it may be necessary to target HIV reservoirs in
anatomic compartments other than blood. This study examined HIV RNA rebound following …
anatomic compartments other than blood. This study examined HIV RNA rebound following …
Compartmentalization, viral evolution, and viral latency of HIV in the CNS
MM Bednar, CB Sturdevant, LA Tompkins… - Current HIV/AIDS …, 2015 - Springer
Human immunodeficiency virus type 1 (HIV-1) infection occurs throughout the body and can
have dramatic physical effects, such as neurocognitive impairment in the central nervous …
have dramatic physical effects, such as neurocognitive impairment in the central nervous …
Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection
G Schnell, RW Price, R Swanstrom… - Journal of virology, 2010 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1)-associated dementia (HAD) is a severe
neurological disease that affects a subset of HIV-1-infected individuals. Increased …
neurological disease that affects a subset of HIV-1-infected individuals. Increased …
[HTML][HTML] T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy
HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in
CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine …
CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine …
[HTML][HTML] Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1–associated dementia
G Schnell, S Spudich, P Harrington, RW Price… - PLoS …, 2009 - journals.plos.org
Human immunodeficiency virus type 1 (HIV-1) invades the central nervous system (CNS)
shortly after systemic infection and can result in the subsequent development of HIV-1 …
shortly after systemic infection and can result in the subsequent development of HIV-1 …