Anesthesia and surgery (A+ S) are risk factors for patients to develop postoperative delirium
(POD). However, the pathogenesis of POD remains largely to be determined. We employed …

Postoperative delirium is associated with increased morbidity, mortality and cost. However,
its neuropathogenesis remains largely unknown, partially owing to lack of animal model (s) …

The acute neuroinflammatory response to surgery may play a key pathogenic role in
postoperative delirium (POD). Here, we investigated the contribution of acute postoperative …

Purpose The purpose of this study was to investigate the age-, time-, and brain region-
dependent postoperative neuroinflammatory trajectory, and its association with …

Postoperative delirium (POD) is common in the elderly and associated with poor clinical
outcomes. Reactive oxygen species (ROS) and blood-brain barrier (BBB) damage have …

Postoperative delirium (POD) is a complication characterized by disturbances in attention,
awareness, and cognitive function that occur shortly after surgery or emergence from …

Postoperative delirium (POD) is an acute cognitive dysfunction that is mainly characterized
by memory impairment and disturbances in consciousness. POD can prolong the hospital …

Objective To establish a clinically relevant mouse model of perioperative delirium. Methods
Aged C57BL/6J mice were tested at baseline in the Y-maze novel arm preference, buried …

Postoperative delirium (POD) is a neurobehavioral syndrome caused by dysfunction of
neural activity mainly in elderly people. POD is not uncommon, but under-recognized, and …

Purpose Neuroinflammation may contribute to the pathogenesis of the cognitive symptoms
of postoperative delirium (POD) and its subsequent long-term cognitive impairment …