The fabrication of tissue engineering scaffolds necessitates amalgamation of a multitude of
attributes including a desirable porosity to encourage vascular invasion, desired surface …

Tissue engineering in vitro and in vivo involves the interaction of cells with a material
surface. The nature of the surface can directly influence cellular response, ultimately …

In the process of bone regeneration, new bone formation is largely affected by physico-
chemical cues in the surrounding microenvironment. Tissue cells reside in a complex …

Bone tissue engineering utilizes three critical elements–cells, scaffolds, and bioactive factors–
to recapitulate the bone tissue microenvironment, inducing the formation of new bone …

The development of synthetic materials and their use in tissue engineering applications
hasattracted much attention in recent years as an option for trabecular bone grafting …

Bone fractures are common in clinics and the demand for effective repair material is high.
Unfortunately, limited graft availability, donor site morbidities, unpredictable clinical …

Bone defect repair is a complex process of bone regeneration. Bone substitute implanted at
the bone defect sites act as three-dimensional scaffolds that guide and promote bone …

Implant surfaces play important roles in regulating protein adsorption and determining
subsequent cell responses, including cell attachment, proliferation, migration and …

Key features of bone tissue structure and composition are capable of directing cellular
behavior toward the generation of new bone tissue. Bone tissue, as well as materials …

OBJECTIVE: This review surveys new developments in bone tissue engineering, specifically
focusing on the promising role of nanotechnology and describes future avenues of research …