Improving screening and treatment options for patients with epithelial ovarian cancer has
been a major challenge in cancer research. Development of novel diagnostic and …

High grade serous ovarian cancer (HGSOC) is the most frequent type of ovarian cancer.
Most patients have primary response to platinum-based chemotherapy but frequently …

Background Cell line models have proven to be effective tools to investigate a variety of
ovarian cancer features. Due to the limited number of cell lines, particularly of the serous …

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial,
with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered …

High-grade serous ovarian carcinoma (HGSOC) is a lethal disease for which improved
screening and treatment strategies are urgently needed. Progress in these areas is impeded …

Fallopian tube secretory epithelial cells (FTSECs) have been suggested to be the source of
high-grade serous ovarian carcinoma (HGSOC). Although several genetic alterations are …

High-grade serous ovarian carcinoma (HGSOC) is the fifth leading cause of cancer-related
deaths of women in the United States. Disease-associated mutations have been identified …

High-grade serous carcinoma (HGSC) is the most lethal ovarian cancer histotype. The
fallopian tube secretory epithelial cells (FTSECs) are a proposed progenitor cell type …

Genomic analysis of ovarian cancer cell lines has revealed a panel that best represents the
most common ovarian cancer subtype, high-grade serous ovarian cancer (HGSOC) …

High-grade serous ovarian carcinoma (HGSOC) is the most frequent histological type of
ovarian cancer and the one with worst prognosis. Unfortunately, the majority of established …